2-(Trifluoromethyl)-6-iodopyridine

2-(Trifluoromethyl)-6-iodopyridine - Names and Identifiers

Name	2-iodo-6-(trifluoromethyl)pyridine
Synonyms	2-Iodo-6-(trifluoromethyl)pyridine 2-iodo-6-(trifluoromethyl)pyridine 2-(trifluoromethyl)-6-iodopyridine 2-(Trifluoromethyl)-6-iodopyridine Pyridine, 2-iodo-6-(trifluoromethyl)-
CAS	100366-74-3
InChI	InChI=1/C6H3F3IN/c7-6(8,9)4-2-1-3-5(10)11-4/h1-3H

2-(Trifluoromethyl)-6-iodopyridine - Physico-chemical Properties

Molecular Formula	C6H3F3IN
Molar Mass	272.99
Density	1.974
Boling Point	206℃
Flash Point	79℃
Vapor Presure	0.345mmHg at 25°C
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Sensitive	Irritant
Refractive Index	1.523
MDL	MFCD11100178

2-(Trifluoromethyl)-6-iodopyridine - Introduction

2-iodo-6-trifluoromethylpyridine (-) is an organic compound with the chemical formula of C6H3F3IN. The following is a description of its nature, use, formulation and safety information:

Nature:
2-Iodo-6-trifluoromethylpyridine was a solid having a white to pale yellow crystalline form. It has a high melting point and boiling point, and is stable at room temperature. It has good solubility in organic solvents. This compound has strong hygroscopicity.

Use:
2-iodo-6-trifluoromethylpyridine is widely used in the field of organic synthesis and medicine. It can be used as a ligand for metal-catalyzed reactions, such as iron-catalyzed synthesis of nitrogen hydrides. In addition, it can also be used in the synthesis of other organic compounds, such as pesticides and pharmaceutical intermediates.

Preparation Method:
2-iodo-6-trifluoromethylpyridine can be obtained by reacting pyridine iodide with a trifluoromethylating reagent. The specific preparation method is as follows:
Pyridine iodide is dissolved in a suitable solvent, and then an appropriate amount of trifluoromethylating reagent is added. The reaction mixture is reacted under appropriate conditions for a short reaction time. Finally, the pure product is isolated by crystallization and filtration.

Safety Information:
2-iodo-6-trifluoromethylpyridine should be properly stored away from heat sources and oxidizing agents. During operation, necessary personal protective measures should be taken, such as wearing protective glasses and gloves. During handling and storage, safety practices should be followed to avoid contact with skin and inhalation of vapors. In case of accidental contact, rinse immediately with plenty of water and seek medical attention if necessary. When disposing of waste, it should be disposed of in accordance with local regulations.

Last Update：2024-04-09 21:00:56