2-(Trifluoromethyl)b
2-(trifluoromethyl)benzylamine
CAS: 3048-01-9
Molecular Formula: C8H8F3N
2-(Trifluoromethyl)b - Names and Identifiers
| Name | 2-(trifluoromethyl)benzylamine |
| Synonyms | 2-(Trifluoromethyl)b 2-Trifluoromethylbenzylamine 0-(Trifluoromethyl)benzylamine 2-(TRIFLUOROMETHYL)BENZYLAMINE 2-(trifluoromethyl)benzylamine 2-(Trifluoromethyl)benzenemethanamine [2-(trifluoroMethyl)phenyl]MethanaMine 2-(Trifluoromethyl)benzylamine,2-(Aminomethyl)benzotrifluoride |
| CAS | 3048-01-9 |
| EINECS | 221-258-2 |
| InChI | InChI=1/C8H8F3N/c9-8(10,11)7-4-2-1-3-6(7)5-12/h1-4H,5,12H2/p+1 |
2-(Trifluoromethyl)b - Physico-chemical Properties
| Molecular Formula | C8H8F3N |
| Molar Mass | 175.15 |
| Density | 1.249g/mLat 25°C(lit.) |
| Boling Point | 108-110°C 64mm |
| Flash Point | 157°F |
| Vapor Presure | 0.971mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.249 |
| Color | Clear colorless to light yellow |
| BRN | 1103424 |
| pKa | 8.27±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.471(lit.) |
2-(Trifluoromethyl)b - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R22 - Harmful if swallowed R34 - Causes burns R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 2735 8/PG 3 |
| WGK Germany | 2 |
| FLUKA BRAND F CODES | 10-34 |
| HS Code | 29214990 |
| Hazard Note | Corrosive |
| Hazard Class | 8 |
| Packing Group | III |
2-(Trifluoromethyl)b - Introduction
2-(trifluoromethyl)benzylamine is an organic compound with the chemical formula C8H8F3N. It is a colorless liquid and has a strong ammonia odor.
2-(trifluoromethyl)benzylamine has important applications in the field of drug research. It is used as an intermediate in drug synthesis, particularly in the development of antidepressant and antipsychotic drugs. It is also used in areas such as synthetic pesticides and dyes.
The process for the preparation of 2-(trifluoromethyl)benzylamine generally comprises the reaction of benzylamine in the presence of a trifluoromethylating reagent such as sodium trifluoromethyliodide. The reaction process may require the control of reaction solvent, reaction temperature and reaction time.
Regarding safety information, 2-(trifluoromethyl)benzylamine is an irritating compound. It needs to be operated in a well-ventilated environment, avoiding skin contact and inhalation. Wear appropriate personal protective equipment such as protective gloves, goggles and protective clothing during use or handling. In addition, it should be stored in a sealed container, away from fire and oxidizing agents. When waste is disposed of, it should be disposed of in accordance with local regulations. In order to ensure safety, please follow the relevant safety operation guidelines.
2-(trifluoromethyl)benzylamine has important applications in the field of drug research. It is used as an intermediate in drug synthesis, particularly in the development of antidepressant and antipsychotic drugs. It is also used in areas such as synthetic pesticides and dyes.
The process for the preparation of 2-(trifluoromethyl)benzylamine generally comprises the reaction of benzylamine in the presence of a trifluoromethylating reagent such as sodium trifluoromethyliodide. The reaction process may require the control of reaction solvent, reaction temperature and reaction time.
Regarding safety information, 2-(trifluoromethyl)benzylamine is an irritating compound. It needs to be operated in a well-ventilated environment, avoiding skin contact and inhalation. Wear appropriate personal protective equipment such as protective gloves, goggles and protective clothing during use or handling. In addition, it should be stored in a sealed container, away from fire and oxidizing agents. When waste is disposed of, it should be disposed of in accordance with local regulations. In order to ensure safety, please follow the relevant safety operation guidelines.
Last Update：2024-04-09 20:52:54
