2-(benzylthio)aniline
2-(benzylthio)aniline
CAS: 6325-92-4
Molecular Formula: C13H13NS
2-(benzylthio)aniline - Names and Identifiers
| Name | 2-(benzylthio)aniline |
| Synonyms | NSC 31147 Einecs 228-690-0 2-(benzylthio)aniline |
| CAS | 6325-92-4 |
| EINECS | 228-690-0 |
| InChI | InChI=1/C22H15FN2O4/c23-15-4-1-13(2-5-15)22-25-17-12-16(6-8-18(17)29-22)24-21(26)14-3-7-19-20(11-14)28-10-9-27-19/h1-8,11-12H,9-10H2,(H,24,26) |
2-(benzylthio)aniline - Physico-chemical Properties
| Molecular Formula | C13H13NS |
| Molar Mass | 215.31 |
| Density | 1.41g/cm3 |
| Boling Point | 487.1°C at 760 mmHg |
| Flash Point | 248.4°C |
| Vapor Presure | 1.22E-09mmHg at 25°C |
| Refractive Index | 1.678 |
2-(benzylthio)aniline - Introduction
2-(benzylthio)aniline is an organic compound with the chemical formula C13H11NS. The following is a description of the properties, uses, preparation and safety information of the compound:
1. nature:
-Appearance: 2-(benzylthio)aniline is a colorless to light yellow solid.
-Solubility: It is soluble in organic solvents such as alcohols, ethers and dimethylformamide, but insoluble in water.
2. use:
2-(benzylthio)aniline has important application value in organic synthesis and can be used as the following aspects:
-intermediates for the synthesis of organic dyes and fluorescent dyes.
-as a catalyst for chemical reactions.
-Play a role in the preparation of photosensitive dyes and photosensitive polymers.
-May have antibacterial and anticancer activity in the field of medicine.
3. Preparation method:
2-(benzylthio)aniline can be synthesized in several ways, such:
-Through nucleophilic substitution reaction: 2-bromobenzoic acid and sulfuryl chloride are reacted to obtain 2-aminophenylformic acid sulfuryl chloride, which is then condensed with phenylacetylene, and finally reduced by hydrogenation to obtain the product.
-Synthesis by the condensation reaction of amines and thiols.
4. Safety Information: The chemical properties of
- 2-(benzylthio)aniline are not fully understood, so appropriate laboratory procedures and precautions, including gloves and safety glasses, should be taken when using them.
-The compound may be irritating to the skin and eyes, and direct contact should be avoided.
-When storing and handling, it should be kept away from combustibles, strong oxidants and strong acids.
Please note that the information presented above is for informational purposes only and is based on what is currently known. In the specific use and operation, it is recommended to refer to the relevant literature and laboratory safety guidelines, and follow the relevant laws and regulations.
1. nature:
-Appearance: 2-(benzylthio)aniline is a colorless to light yellow solid.
-Solubility: It is soluble in organic solvents such as alcohols, ethers and dimethylformamide, but insoluble in water.
2. use:
2-(benzylthio)aniline has important application value in organic synthesis and can be used as the following aspects:
-intermediates for the synthesis of organic dyes and fluorescent dyes.
-as a catalyst for chemical reactions.
-Play a role in the preparation of photosensitive dyes and photosensitive polymers.
-May have antibacterial and anticancer activity in the field of medicine.
3. Preparation method:
2-(benzylthio)aniline can be synthesized in several ways, such:
-Through nucleophilic substitution reaction: 2-bromobenzoic acid and sulfuryl chloride are reacted to obtain 2-aminophenylformic acid sulfuryl chloride, which is then condensed with phenylacetylene, and finally reduced by hydrogenation to obtain the product.
-Synthesis by the condensation reaction of amines and thiols.
4. Safety Information: The chemical properties of
- 2-(benzylthio)aniline are not fully understood, so appropriate laboratory procedures and precautions, including gloves and safety glasses, should be taken when using them.
-The compound may be irritating to the skin and eyes, and direct contact should be avoided.
-When storing and handling, it should be kept away from combustibles, strong oxidants and strong acids.
Please note that the information presented above is for informational purposes only and is based on what is currently known. In the specific use and operation, it is recommended to refer to the relevant literature and laboratory safety guidelines, and follow the relevant laws and regulations.
Last Update：2024-04-09 20:49:11
