2-(chloromethyl)-4,6-dimethoxypyrimidine

2-(chloromethyl)-4,6-dimethoxypyrimidine - Names and Identifiers

Name	2-(chloromethyl)-4,6-dimethoxypyrimidine
Synonyms	2-chloroMethyl-4,6-diMethoxylpyMidine 2-Chloromethyl-4,6-dimethoxypyrimidine 2-(chloromethy)-4,6-dimethoxypyrimidine 2-(CHLOROMETHYL)-4,6-DIMETHOXYPYRIMIDINE 2-(chloromethyl)-4,6-dimethoxypyrimidine PYRIMIDINE, 2-(CHLOROMETHYL)-4,6-DIMETHOXY 2-(Chloromethyl)-4,6-dimethoxy-1,3-diazine (4,6-DIMETHOXYPYRIMIDIN-2-YL)METHYL CHLORIDE
CAS	114108-86-0
InChI	InChI=1/C7H9ClN2O2/c1-11-6-3-7(12-2)10-5(4-8)9-6/h3H,4H2,1-2H3

2-(chloromethyl)-4,6-dimethoxypyrimidine - Physico-chemical Properties

Molecular Formula	C7H9ClN2O2
Molar Mass	188.61
Density	1.244±0.06 g/cm3(Predicted)
Melting Point	39-42
Boling Point	271.0±30.0 °C(Predicted)
Flash Point	117.668°C
Vapor Presure	0.011mmHg at 25°C
pKa	0.43±0.30(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.513

2-(chloromethyl)-4,6-dimethoxypyrimidine - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Toxic/Irritant

2-(chloromethyl)-4,6-dimethoxypyrimidine - Introduction

2-(chloromethyl)-4,6-dimethoxypyrimidine is an organic compound, the chemical formula is C9H11ClN2O2, the structure has chloromethyl and two methoxy substituted benzene rings and pyrimidine ring. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless solid
-melting point: about 132-137 ℃
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide

Use:
-PHARMACEUTICAL RESEARCH: 2-(chloromethyl)-4,6-dimethoxypyrimidine is an important pyrimidine derivative commonly used in pharmaceutical research as a precursor for potential anticancer drugs or inhibitors.
-Pesticide manufacturing: The compound can also be used as one of the intermediates in the manufacture of pesticides.

Method:
- 2-(chloromethyl)-4,6-dimethoxypyrimidine is usually obtained by reacting pyrimidine and its derivatives with chloromethylates such as chloromethanol or chloromethyldimethylaminomethane.

Safety Information:
- 2-(chloromethyl)-4,6-dimethoxypyrimidine should avoid contact with skin and eyes, and avoid inhalation or intake.
-Use with appropriate personal protective equipment, such as gloves and masks.
-It should be used in a well-ventilated place to avoid prolonged exposure to the air.
-If accidental contact or inhalation, should promptly clean the affected parts, and seek medical advice.

Last Update：2024-04-09 02:00:41