2-(propan-2-yl)pyrimidine-5-carbaldehyde

2-(propan-2-yl)pyrimidine-5-carbaldehyde - Names and Identifiers

Name	2-(1-methylethyl)pyrimidine-5-carbaldehyde
Synonyms	2-Isopropylpyrimidine-5-carbaldehyde 2-(propan-2-yl)pyrimidine-5-carbaldehyde 2-(1-methylethyl)pyrimidine-5-carbaldehyde 5-PyriMidinecarboxaldehyde,2-(1-Methylethyl)- 5-pyrimidinecarboxaldehyde, 2-(1-methylethyl)- 5-Pyrimidinecarboxaldehyde, 2-(1-methylethyl)- (9CI)
CAS	312263-48-2
InChI	InChI=1/C8H10N2O/c1-6(2)8-9-3-7(5-11)4-10-8/h3-6H,1-2H3

2-(propan-2-yl)pyrimidine-5-carbaldehyde - Physico-chemical Properties

Molecular Formula	C8H10N2O
Molar Mass	150.18
Density	1.091±0.06 g/cm3(Predicted)
Boling Point	230.0±13.0 °C(Predicted)
Flash Point	95.6°C
Vapor Presure	0.0676mmHg at 25°C
pKa	0.23±0.22(Predicted)
Refractive Index	1.542

2-(propan-2-yl)pyrimidine-5-carbaldehyde - Risk and Safety

Hazard Class

IRRITANT

2-(propan-2-yl)pyrimidine-5-carbaldehyde - Introduction

2-(1-methyllethyl) pyrimidine-5-carbaldehyde is an organic compound with the chemical formula C8H12N2O. It is a yellow to orange solid with a peculiar smell.

This compound can be used as a pharmaceutical intermediate and a reagent for organic synthesis. It is often used in the field of medicine for the synthesis of anti-cancer drugs and antiviral drugs. In addition, it is also used in the preparation of dyes, fragrances and pesticides.

Preparation of 2-(1-methyllethyl) pyrimidine-5-carbaldehyde can be obtained by reaction of isopropylamine and 2-bromoacetone. First, under appropriate reaction conditions, isopropylamine is reacted with 2-bromoacetone to produce 2-isopropylpyrimidine. The 2-isopropylpyrimidine is then reacted with an oxidizing agent such as cupric borate to give 2-(1-methylethyl)pyrimidine-5-carbaldehyde.

Regarding safety information, 2-(1-methyllethyl) pyrimidine-5-carbaldehyde are generally relatively safe under normal conditions of use. However, inhalation, ingestion or contact with skin and eyes should be avoided. When in use, appropriate personal protective measures should be taken, such as wearing gloves and goggles. Store at low temperatures and avoid contact with oxidants or flammable materials. If an accident occurs, seek medical attention immediately.

Last Update：2024-04-09 21:01:54