2-(pyridin-2-yl)-5-bromopyridine
5-BROMO-2,2'-BIPYRIDINE
CAS: 15862-19-8
Molecular Formula: C10H7BrN2
2-(pyridin-2-yl)-5-bromopyridine - Names and Identifiers
| Name | 5-BROMO-2,2'-BIPYRIDINE |
| Synonyms | 5-BroMo-2,2'-bipyridyl 5-BROMO-2,2'-BIPYRIDINE 2,2'-Bipyridine,5-broMo- 5-Bromo-[2,2']bipyridinyl 3-Bromo-6-(2-pyridyl)pyridine 2-(2-Pyridyl)-5-broMopyridine 2-(pyridin-2-yl)-5-bromopyridine |
| CAS | 15862-19-8 |
| InChI | InChI=1/C10H7BrN2/c11-8-4-5-10(13-7-8)9-3-1-2-6-12-9/h1-7H |
2-(pyridin-2-yl)-5-bromopyridine - Physico-chemical Properties
| Molecular Formula | C10H7BrN2 |
| Molar Mass | 235.08 |
| Density | 1.493±0.06 g/cm3(Predicted) |
| Melting Point | 73 °C |
| Boling Point | 322.4±27.0 °C(Predicted) |
| Flash Point | 148.8°C |
| Vapor Presure | 0.000527mmHg at 25°C |
| pKa | 3.55±0.22(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.612 |
2-(pyridin-2-yl)-5-bromopyridine - Introduction
5-BROMO-2,2 '-BIPYRIDINE is an organic compound with the chemical formula C11H7BrN. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 5-BROMO-2,2 '-BIPYRIDINE is a white or off-white crystal.
-Solubility: It is soluble in most organic solvents, such as ethers, alcohols and ketones, but insoluble in water.
-Melting point: Its melting point is about 127-130°C.
-Chemical properties: The compound is prone to electrophilic substitution reactions, such as amino substitution reactions with substitutable amino compounds.
Use:
- 5-BROMO-2,2 '-BIPYRIDINE can be used as a starting material or intermediate in organic synthesis reactions.
-The compound has certain application potential in the field of medicine, such as as a synthetic intermediate for antibacterial drugs.
Method:
The preparation of 5-BROMO-2,2 '-BIPYRIDINE is usually carried out by one of the following methods:
1. Reaction of BIPYRIDINE with bromine: reaction of BIPYRIDINE with bromine, heating and stirring to obtain 5-BROMO-2,2 '-BIPYRIDINE product from the reaction system.
2. Bipyridine bromide: The compound is prepared by direct reaction of bipyridine with bromine.
Safety Information:
- 5-BROMO-2,2 '-BIPYRIDINE is irritating to skin and eyes, and contact with skin and eyes should be avoided.
-Wear appropriate personal protective equipment such as lab gloves and safety glasses during operation.
-If you come into contact with this compound, rinse the affected area immediately with plenty of water and seek medical advice.
-Use and store this compound under safe, ventilated conditions and avoid inhaling its volatiles.
-Waste disposal should follow local regulations to avoid environmental pollution.
Nature:
-Appearance: 5-BROMO-2,2 '-BIPYRIDINE is a white or off-white crystal.
-Solubility: It is soluble in most organic solvents, such as ethers, alcohols and ketones, but insoluble in water.
-Melting point: Its melting point is about 127-130°C.
-Chemical properties: The compound is prone to electrophilic substitution reactions, such as amino substitution reactions with substitutable amino compounds.
Use:
- 5-BROMO-2,2 '-BIPYRIDINE can be used as a starting material or intermediate in organic synthesis reactions.
-The compound has certain application potential in the field of medicine, such as as a synthetic intermediate for antibacterial drugs.
Method:
The preparation of 5-BROMO-2,2 '-BIPYRIDINE is usually carried out by one of the following methods:
1. Reaction of BIPYRIDINE with bromine: reaction of BIPYRIDINE with bromine, heating and stirring to obtain 5-BROMO-2,2 '-BIPYRIDINE product from the reaction system.
2. Bipyridine bromide: The compound is prepared by direct reaction of bipyridine with bromine.
Safety Information:
- 5-BROMO-2,2 '-BIPYRIDINE is irritating to skin and eyes, and contact with skin and eyes should be avoided.
-Wear appropriate personal protective equipment such as lab gloves and safety glasses during operation.
-If you come into contact with this compound, rinse the affected area immediately with plenty of water and seek medical advice.
-Use and store this compound under safe, ventilated conditions and avoid inhaling its volatiles.
-Waste disposal should follow local regulations to avoid environmental pollution.
Last Update：2024-04-09 15:17:53
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CAS: 15862-19-8
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