2-(t-Butyldimethylsilyloxy)EthylTrifluoromethanesulfonate
2-(tert-butyldimethylsilyl)oxyl alcohol trifluorin methanesulfonate
CAS: 164162-36-1
Molecular Formula: C9H19F3O4SSi
2-(t-Butyldimethylsilyloxy)EthylTrifluoromethanesulfonate - Names and Identifiers
2-(t-Butyldimethylsilyloxy)EthylTrifluoromethanesulfonate - Physico-chemical Properties
| Molecular Formula | C9H19F3O4SSi |
| Molar Mass | 308.39 |
| Density | 1.172 |
| Boling Point | 253℃ |
| Flash Point | 107℃ |
| Physical and Chemical Properties | Appearance: colorless transparent liquid |
| Use | For Organic synthesis |
2-(t-Butyldimethylsilyloxy)EthylTrifluoromethanesulfonate - Introduction
2-(tert-butyldimethylsilyl)oxyl alcohol trifluorin methanosulfonate is an organic compound with the formula C13H27F3O4SSi, often abbreviated as "TBDMSOTf".
Nature:
1. Appearance is colorless to yellowish liquid.
2. Has good solubility, soluble in most organic solvents.
3. It has high stability and thermal stability.
Use:
1. As a protecting group in organic synthesis:
- TBDMSOTf can be used as a reagent for protecting functional groups such as amino, hydroxyl, and carboxyl groups, and can be used to synthesize compounds or protect active sites in compounds.
2. For Catalytic reagents in organic synthesis:
- TBDMSOTf is used as a catalyst in some organic reactions to promote the reaction.
3. For fluoromethylsulfonate free radical polymerization initiator.
4. Application in biomedical research:
-Because it can react with bioactive molecules, it can be used in drug development, natural product modification and other fields.
Method:
TBDMSOTf is generally prepared by reacting 2-(tert-butyldimethylsilyl) oxyethanol with trifluoromethanesulfonic acid.
Safety Information:
1. TBDMSOTf is an organic synthetic reagent. Appropriate personal protective equipment should be worn during operation to prevent contact with skin, eyes and inhalation of gas.
2. The compound may be harmful to the environment and should be avoided from entering the environment.
3. In the process of storage and transportation should pay attention to prevent fire and high temperature.
4. Use the process to follow the correct method of operation, to avoid mixing with other chemicals to cause the reaction.
Nature:
1. Appearance is colorless to yellowish liquid.
2. Has good solubility, soluble in most organic solvents.
3. It has high stability and thermal stability.
Use:
1. As a protecting group in organic synthesis:
- TBDMSOTf can be used as a reagent for protecting functional groups such as amino, hydroxyl, and carboxyl groups, and can be used to synthesize compounds or protect active sites in compounds.
2. For Catalytic reagents in organic synthesis:
- TBDMSOTf is used as a catalyst in some organic reactions to promote the reaction.
3. For fluoromethylsulfonate free radical polymerization initiator.
4. Application in biomedical research:
-Because it can react with bioactive molecules, it can be used in drug development, natural product modification and other fields.
Method:
TBDMSOTf is generally prepared by reacting 2-(tert-butyldimethylsilyl) oxyethanol with trifluoromethanesulfonic acid.
Safety Information:
1. TBDMSOTf is an organic synthetic reagent. Appropriate personal protective equipment should be worn during operation to prevent contact with skin, eyes and inhalation of gas.
2. The compound may be harmful to the environment and should be avoided from entering the environment.
3. In the process of storage and transportation should pay attention to prevent fire and high temperature.
4. Use the process to follow the correct method of operation, to avoid mixing with other chemicals to cause the reaction.
Last Update：2024-04-09 02:00:42
