2-(tert-butyl)-4,4,5,5-tetramthyl-1,3,2-dioxaborolane - Names and Identifiers
Name | 2-tert-butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Synonyms | Pinacol tert butyl borate tert-Butylboronic acid pinacol ester TERT-BUTYLBORONIC ACID PINACOL ESTER 2-tert-butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(tert-butyl)-4,4,5,5-tetramthyl-1,3,2-dioxaborolane 2-(tert-Butyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 2-(1,1-dimethylethyl)-4,4,5,5-tetramethyl-
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CAS | 99810-76-1
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InChI | InChI=1/C10H21BO2/c1-8(2,3)11-12-9(4,5)10(6,7)13-11/h1-7H3 |
2-(tert-butyl)-4,4,5,5-tetramthyl-1,3,2-dioxaborolane - Physico-chemical Properties
Molecular Formula | C10H21BO2
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Molar Mass | 184.08 |
Density | 0.87 |
Boling Point | 60-61℃ |
Flash Point | 66.604°C |
Vapor Presure | 0.908mmHg at 25°C |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.4105 |
2-(tert-butyl)-4,4,5,5-tetramthyl-1,3,2-dioxaborolane - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Note | Irritant |
2-(tert-butyl)-4,4,5,5-tetramthyl-1,3,2-dioxaborolane - Introduction
2-tert-butyl-4,4,5, 5-tetraethyl-1, 3,2-dioxaborolane is an organic compound with the chemical formula C9H19BO2. The following is a description of its nature, use, formulation and safety information:
Nature:
1. 2-tert-butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a colorless liquid, insoluble in water at room temperature.
2. It has low volatility and low melting point, and can be dissolved in some organic solvents, such as ether and toluene.
3. It is stable in the air, but can be oxidized by oxidants.
Use:
1. 2-tert-butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is commonly used as an organic boron reagent in organic synthesis for various catalytic reactions, such as Suzuki coupling reaction, Sonogashira coupling reaction and Heck reaction, etc.
2. It is also used as a protecting group in organic synthesis.
Preparation Method:
2-tert-butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane can be prepared by reacting 2,4, 5-trimethyl-3-ethoxypentafluorophenone with diethyl borate.
Safety Information:
1. In the use and operation of 2-tert-butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, it is necessary to take appropriate protective measures, such as wearing appropriate protective gloves and glasses.
2. It is a flammable substance and should be kept away from fire sources and open flames.
3. When storing 2-tert-butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, it should be sealed and stored in a cool, dry and well-ventilated place.
Last Update:2024-04-10 22:29:15