2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)aniline
2-Amino-5-(trifluoromethyl)phenylboronic acid, pinacol ester
CAS: 1058062-64-8
Molecular Formula: C13H17BF3NO2
2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)aniline - Names and Identifiers
2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)aniline - Physico-chemical Properties
| Molecular Formula | C13H17BF3NO2 |
| Molar Mass | 287.09 |
| Storage Condition | 2-8°C(protect from light) |
2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)aniline - Introduction
2-Amino-5-trifluoromethylphenylboronic acid ester is an organic compound with the chemical formula C8H7BF3NO2. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
2-Amino-5-trifluoromethylphenylboronic acid ester, also known as Rink Amide Linker or Fmoc-amine linker, is a white powdery solid. It has good solubility and can be dissolved in most organic solvents, such as dimethyl sulfoxide (DMSO), dimethyl formamide (DMF) and so on. It is stable at room temperature, but avoids contact with oxygen.
Use:
2-amino -5-trifluoromethylphenylboronic acid ester is often used as an introducing agent for active groups in organic synthesis. It can be used in the synthesis of peptides and oligomeric peptides as an amino protecting group. It can also be used to synthesize drugs and bioactive molecules. Because it can be used as a linking group in peptide synthesis, it has a wide range of applications in the field of drug development and biochemistry.
Preparation Method:
2-amino -5-trifluoromethyl benzene boronic acid ester of the preparation method has many kinds. A common method is to add 2-amino -5-trifluoromethylbenzeneboronic acid and benzonol ester to the reaction solution, and then go through a series of activation and protection steps to finally obtain the target product.
Safety Information:
2-Amino-5-trifluoromethylphenylboronic acid ester is relatively safe under normal conditions of use. However, it is a chemical that is potentially dangerous. During use, direct contact with skin and eyes should be avoided, and personal protective equipment such as gloves and goggles should be worn if possible. In addition, it should be used in a well-ventilated place to avoid inhalation of dust. If accidentally splashed into the eyes or skin, rinse immediately with plenty of water and seek medical help.
Nature:
2-Amino-5-trifluoromethylphenylboronic acid ester, also known as Rink Amide Linker or Fmoc-amine linker, is a white powdery solid. It has good solubility and can be dissolved in most organic solvents, such as dimethyl sulfoxide (DMSO), dimethyl formamide (DMF) and so on. It is stable at room temperature, but avoids contact with oxygen.
Use:
2-amino -5-trifluoromethylphenylboronic acid ester is often used as an introducing agent for active groups in organic synthesis. It can be used in the synthesis of peptides and oligomeric peptides as an amino protecting group. It can also be used to synthesize drugs and bioactive molecules. Because it can be used as a linking group in peptide synthesis, it has a wide range of applications in the field of drug development and biochemistry.
Preparation Method:
2-amino -5-trifluoromethyl benzene boronic acid ester of the preparation method has many kinds. A common method is to add 2-amino -5-trifluoromethylbenzeneboronic acid and benzonol ester to the reaction solution, and then go through a series of activation and protection steps to finally obtain the target product.
Safety Information:
2-Amino-5-trifluoromethylphenylboronic acid ester is relatively safe under normal conditions of use. However, it is a chemical that is potentially dangerous. During use, direct contact with skin and eyes should be avoided, and personal protective equipment such as gloves and goggles should be worn if possible. In addition, it should be used in a well-ventilated place to avoid inhalation of dust. If accidentally splashed into the eyes or skin, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 20:45:29
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CAS: 1058062-64-8
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