2-ACETAMIDO-5-FLUORO-4-PICOLINE

2-ACETAMIDO-5-FLUORO-4-PICOLINE - Names and Identifiers

Name	N-(5-fluoro-4-methylpyridin-2-yl)acetamide
Synonyms	2-ACETAMIDO-5-FLUORO-4-PICOLINE 2-Acetamido-5-fluoro-4-picoline 2-ACETAMIDO-5-FLUORO-4-METHYLPYRIDINE N-(5-fluoro-4-methylpyridin-2-yl)acetamide N-(5-Fluoro-4-methylpyridin-2-yl)acetamide N-(5-Fluoro-4-methyl-2-pyridinyl)-acetamide Acetamide, N-(5-fluoro-4-methyl-2-pyridinyl)- acetamide, N-(5-fluoro-4-methyl-2-pyridinyl)-
CAS	475060-21-0
InChI	InChI=1/C8H9FN2O/c1-5-3-8(11-6(2)12)10-4-7(5)9/h3-4H,1-2H3,(H,10,11,12)

2-ACETAMIDO-5-FLUORO-4-PICOLINE - Physico-chemical Properties

Molecular Formula	C8H9FN2O
Molar Mass	168.17
Density	1.234g/cm³
Boling Point	321.4°C at 760 mmHg
Flash Point	148.2°C
Vapor Presure	0.000299mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.55

2-ACETAMIDO-5-FLUORO-4-PICOLINE - Introduction

N-(+) acetamide is an organic compound with a chemical formula of C9H10FN2O and a molecular weight of 180.19g/mol.

It is a solid with a white or light yellow crystalline powder. Its melting point is about 109-111°C.

N-(Br) acetamide is generally used as an intermediate in organic synthesis. It can be used as a starting material for the synthesis of drugs, and can also be used for the synthesis of other organic compounds.

It can be obtained by the following synthetic methods:
2-Acetylaminopyridine was obtained by reacting 2-picolinic acid with acetyl chloride. The 2-acetamidopyridine is then reacted with boron pentafluoride to produce 2-acetamido-5-fluoropyridine. Finally, 2-acetylamino-5-fluoropyridine is reacted with formyl chloride to give N-(fluoryl) acetamide.

For safety information, N-acetamide should be considered hazardous. Observe appropriate protective measures during operation, including wearing protective glasses, protective clothing and gloves. When stored, it should be kept in a dry, cool place. Avoid contact with oxidizing agents. In case of contact with skin or eyes, rinse with plenty of water and seek medical help.

Last Update：2024-04-09 21:00:56