2-ACETYLAMINO-4-METHYLPYRIDINE

2-ACETYLAMINO-4-METHYLPYRIDINE - Names and Identifiers

Name	N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE
Synonyms	Zinc00331098 2-ACETAMIDO-4-PICOLINE 2-Acetylamino-4-methylpyridine 2-ACETYLAMINO-4-METHYLPYRIDINE N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE N-(4-Methyl-2-pyridinyl)-AcetaMide N-(4-METHYL-PYRIDINE-2-YL)-ACETAMIDE Acetamide,N-(4-methyl-2-pyridinyl)-
CAS	5327-32-2
InChI	InChI=1/C8H10N2O/c1-6-3-4-9-8(5-6)10-7(2)11/h3-5H,1-2H3,(H,9,10,11)

2-ACETYLAMINO-4-METHYLPYRIDINE - Physico-chemical Properties

Molecular Formula	C8H10N2O
Molar Mass	150.18
Density	1.137±0.06 g/cm3(Predicted)
Melting Point	90-94
Boling Point	343.1±22.0 °C(Predicted)
Flash Point	161.3°C
Vapor Presure	7.21E-05mmHg at 25°C
pKa	13.82±0.70(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.572

2-ACETYLAMINO-4-METHYLPYRIDINE - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
HS Code	29333990
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

2-ACETYLAMINO-4-METHYLPYRIDINE - Introduction

N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE is an organic compound. Its chemical formula is C9H11N2O, and its structure contains an acetamide group and a 4-methyl -2-pyridine group.

Properties of N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE:
-Appearance: Colorless or light yellow solid
-Melting point: about 100-105°C
-Solubility: Low solubility in water, but better solubility in some organic solvents.

Use of N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE:
-As an intermediate in organic synthesis, it can be used to synthesize other compounds.
-In the pharmaceutical field, it may be used to synthesize potential drug molecules.

N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE preparation method:
can usually be prepared by the following steps:
1.2-Pyridone is reacted with methyl magnesium bromide (MeMgBr) to obtain 4-methyl -2-pyridyl methyl ketone.
2. The above product is reacted with ethanolamine to generate N-(4-methyl -2-pyridyl) formamide.
3. Finally, N-(4-methyl-2-pyridyl) carboxamide is hydrolyzed under acidic conditions to give N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE.

Safety Information:
Specific safety and acute toxicity data for N-(4-METHYLPYRIDIN-2-YL)ACETAMIDE may be limited, so use requires appropriate laboratory practices. Avoid contact with skin, eyes and respiratory system during use. Immediate contact should be rinsed with plenty of water and seek medical help. In addition, the compound should be stored and handled properly to ensure the safety of the laboratory.

Last Update：2024-04-09 21:00:56