2-AMINO-1-(2,4-DIFLUOROPHENYL)ETHANONE
2-AMINO-2',4'-DIFLUOROACETOPHENONE
CAS: 643029-92-9
Molecular Formula: C8H7F2NO
2-AMINO-1-(2,4-DIFLUOROPHENYL)ETHANONE - Names and Identifiers
| Name | 2-AMINO-2',4'-DIFLUOROACETOPHENONE |
| Synonyms | 2,4-Difluorophenacylamine 3-fluoro-4-methylbenzenethiol a-Amino-2,4-difluoroacetophenone α-Amino-2',4'-difluoroacetophenone α-Amino-2',4'-difluoroacetophenone 2-AMINO-2',4'-DIFLUOROACETOPHENONE 2-Amino-2',4'-Difluoro Acetophenone alpha-Amino-2,4-difluoroacetophenone alpha-Amino-2',4'-difluoroacetophenone 2-AMINO-1-(2,4-DIFLUOROPHENYL)ETHANONE Ethanone, 2-amino-1-(2,4-difluorophenyl)- a-Amino-2,4-difluoroacetophenone hydrochloride 2-amino-1-(2,4-difluorophenyl)ethanone hydrochloride |
| CAS | 643029-92-9 |
| InChI | InChI:1S/C8H7F2NO/c9-5-1-2-6(7(10)3-5)8(12)4-11/h1-3H,4,11H2 |
2-AMINO-1-(2,4-DIFLUOROPHENYL)ETHANONE - Physico-chemical Properties
| Molecular Formula | C8H7F2NO |
| Molar Mass | 171.14 |
| Density | 1.286±0.06 g/cm3(Predicted) |
| Boling Point | 255.9±30.0 °C(Predicted) |
| Flash Point | 129.7°C |
| Vapor Presure | 0.00153mmHg at 25°C |
| pKa | 6.61±0.29(Predicted) |
2-AMINO-1-(2,4-DIFLUOROPHENYL)ETHANONE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
2-AMINO-1-(2,4-DIFLUOROPHENYL)ETHANONE - Introduction
2-AMINO-2 ',4'-DIFLUOROACETOPHENONE is an organic compound with the chemical formula C8H6F2NO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow solid.
-Melting point: 88-90°C.
-Boiling point: 330°C.
-Solubility: Soluble in acid, alkali and organic solvents, such as ethanol and dimethyl sulfoxide.
Use:
- 2-AMINO-2 ',4'-DIFLUOROACETOPHENONE is a commonly used intermediate in organic synthesis and can be used to synthesize other compounds.
-It can be used as a raw material in drug synthesis, such as for the synthesis of non-steroidal anti-inflammatory drugs.
Preparation Method:
2-AMINO-2 ',4'-DIFLUOROACETOPHENONE can be prepared by the following steps:
1. Under alkaline conditions, 2 ',4'-difluoroacetophenone is obtained by reaction with hydrogen fluoride and ethyl acetoacetate.
2. Reaction of 2 ',4'-difluoroacetophenone with ammonia to produce 2-AMINO-2 ',4'-DIFLUOROACETOPHENONE.
Safety Information:
- 2-AMINO-2 ',4'-DIFLUOROACETOPHENONE is generally stable under normal operating conditions, but contact with strong oxidants should be avoided.
-Wear appropriate personal protective equipment such as gloves, safety glasses and protective masks when handling and using the compound.
-Should not inhale the dust or vapor of the compound, and should be operated in a well-ventilated place.
-If swallowed or in contact with skin, rinse immediately with water and seek medical help.
Nature:
-Appearance: Colorless to light yellow solid.
-Melting point: 88-90°C.
-Boiling point: 330°C.
-Solubility: Soluble in acid, alkali and organic solvents, such as ethanol and dimethyl sulfoxide.
Use:
- 2-AMINO-2 ',4'-DIFLUOROACETOPHENONE is a commonly used intermediate in organic synthesis and can be used to synthesize other compounds.
-It can be used as a raw material in drug synthesis, such as for the synthesis of non-steroidal anti-inflammatory drugs.
Preparation Method:
2-AMINO-2 ',4'-DIFLUOROACETOPHENONE can be prepared by the following steps:
1. Under alkaline conditions, 2 ',4'-difluoroacetophenone is obtained by reaction with hydrogen fluoride and ethyl acetoacetate.
2. Reaction of 2 ',4'-difluoroacetophenone with ammonia to produce 2-AMINO-2 ',4'-DIFLUOROACETOPHENONE.
Safety Information:
- 2-AMINO-2 ',4'-DIFLUOROACETOPHENONE is generally stable under normal operating conditions, but contact with strong oxidants should be avoided.
-Wear appropriate personal protective equipment such as gloves, safety glasses and protective masks when handling and using the compound.
-Should not inhale the dust or vapor of the compound, and should be operated in a well-ventilated place.
-If swallowed or in contact with skin, rinse immediately with water and seek medical help.
Last Update：2024-04-09 15:17:59
