2-AMINO-3,5-DIFLUOROPYRIDINE - Names and Identifiers
Name | 2-Amino-3,5-difluoropyridine
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Synonyms | 2-Amino-3,5-difL 3,5-Difluoropyridin-2-aMine 3,5-Difluoro-2-pyridinamine 3,5-Difluoropyridin-2-amine 2-AMINO-3,5-DIFLUOROPYRIDINE 2-Amino-3,5-difluoropyridine 3,5-Difluoro-2-aMinopyridine 3,5-Difluoropyridin-2-ylamine 2-pyridinamine, 3,5-difluoro- 2-Pyridinamine, 3,5-difluoro- 2-Pyridinamine,3,5-difluoro-(9CI)
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CAS | 732306-31-9
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InChI | InChI=1/C5H4F2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9) |
InChIKey | JVLFMTZUPSBCNJ-UHFFFAOYSA-N |
2-AMINO-3,5-DIFLUOROPYRIDINE - Physico-chemical Properties
Molecular Formula | C5H4F2N2
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Molar Mass | 130.1 |
Density | 1.393±0.06 g/cm3(Predicted) |
Melting Point | 55-57 |
Boling Point | 155.8±35.0 °C(Predicted) |
Flash Point | 81℃ |
Vapor Presure | 2.98mmHg at 25°C |
Appearance | Crystallization |
pKa | 1.67±0.49(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.524 |
MDL | MFCD03788760 |
2-AMINO-3,5-DIFLUOROPYRIDINE - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
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UN IDs | UN2811 |
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Note | Harmful/Irritant |
Hazard Class | 6.1 |
Packing Group | III |
2-AMINO-3,5-DIFLUOROPYRIDINE - Introduction
2-Amino-3,5-difluoropyridine(2-Amino-3,5-difluoropyridine) is an organic compound with a chemical formula of C5H3F2N and a molecular weight of 115.08g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- 2-Amino-3,5-difluoropyridine is a colorless solid, soluble in most organic solvents.
-It is a weak base that can react with acids to form salts.
-Its chemical properties are relatively stable, but different reactions may occur in the presence of strong oxidants.
Use:
- 2-Amino-3,5-difluoropyridine is commonly used as an intermediate in organic synthesis to prepare other organic compounds.
-It also has applications in the field of medicine, and can be used to synthesize active fragments of drugs or construct molecular skeletons.
-In the field of pesticides, it can also be used as a synthetic raw material for pesticides or herbicides.
Preparation Method:
- 2-Amino-3,5-difluoropyridine is synthesized by various methods. The common method is to prepare pyrimidine compounds by fluorination reaction.
-Specifically, an amino group can be introduced on the pyrimidine compound, and then fluorine atoms can be introduced at positions 3 and 5 through a fluorination reaction to obtain 2-Amino-3,5-difluoropyridine.
Safety Information:
- 2-Amino-3,5-difluoropyridine is safe under normal circumstances, but as a chemical substance, it is still necessary to pay attention to safe operation.
-When handling, avoid direct contact with skin or inhalation of aerosols, and wear chemical protective gloves and protective glasses.
-When storing, it should be kept in a dry, cool place, and away from fire and oxidizing agents.
-If you come into contact with the compound, you should immediately rinse with plenty of water and seek medical help.
Last Update:2024-04-09 19:05:52