2-Acetyl-6-methoxypyridine
1-(6-methoxypyridin-2-yl)ethanone
CAS: 21190-93-2
Molecular Formula: C8H9NO2
2-Acetyl-6-methoxypyridine - Names and Identifiers
| Name | 1-(6-methoxypyridin-2-yl)ethanone |
| Synonyms | 2-Acetyl-6-methoxypyridine 2-ACETYL-6-METHOXYPYRIDINE 97 1-(6-methoxypyridin-2-yl)ethanone 1-(6-Methoxypyridin-2-yl)ethanone Ethanone, 1-(6-methoxy-2-pyridinyl)- 1-(6-Methoxypyridin-2-yl)ethan-1-one ethanone, 1-(6-methoxy-2-pyridinyl)- |
| CAS | 21190-93-2 |
| InChI | InChI=1/C8H9NO2/c1-6(10)7-4-3-5-8(9-7)11-2/h3-5H,1-2H3 |
2-Acetyl-6-methoxypyridine - Physico-chemical Properties
| Molecular Formula | C8H9NO2 |
| Molar Mass | 151.16 |
| Density | 1.093±0.06 g/cm3(Predicted) |
| Melting Point | 40-44°C |
| Boling Point | 85°C0.2mm Hg |
| Flash Point | 202°F |
| Vapor Presure | 0.159mmHg at 25°C |
| Appearance | Solid |
| pKa | 1.72±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.505 |
| MDL | MFCD08276836 |
2-Acetyl-6-methoxypyridine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
2-Acetyl-6-methoxypyridine - Introduction
1-(6-methoxypyridin-2-yl)ethanone is an organic compound with the chemical formula C9H9NO2. The following describes its nature, use, preparation and safety information:
Nature:
1-(6-methoxypyridin-2-yl)ethanone is a colorless to pale yellow solid with a special smell. It is soluble in many organic solvents such as methanol, ethanol and dichloromethane. It is relatively stable in air, but will decompose when heated or exposed to light.
Use:
1-(6-methoxypyridin-2-yl)ethanone is commonly used as an intermediate in organic synthesis. It can be used to synthesize compounds with biological activity, such as drugs, pesticides and dyes. In addition, it can also be used for application research in the field of organic optoelectronic devices.
Method:
The synthesis method of 1-(6-methoxypyridin-2-yl)ethanone can be obtained by the reaction of pyridine and acetic anhydride. First, pyridine is reacted with an excess of acetic anhydride in a solvent to produce 2-acetylpyridine. Then, 2-acetylpyridine is reacted with methanol to obtain 1-(6-methypyridin-2-yl) ethanone. The reaction is generally carried out at room temperature and usually requires the presence of a catalyst.
Safety Information:
1-(6-methoxypyridin-2-yl)ethanone is generally relatively safe under correct use and storage. However, it is still an organic compound, so appropriate safety measures need to be taken. Wear appropriate protective gloves, goggles, and protective clothing when handling the compound. Avoid inhaling its dust or contact with skin. If contact occurs, rinse immediately with plenty of water. In addition, the compound should be stored in a dry, well-ventilated place, away from combustibles and oxidants. Specific recommendations for safe handling and storage should refer to the relevant safety data sheet for the chemical.
Nature:
1-(6-methoxypyridin-2-yl)ethanone is a colorless to pale yellow solid with a special smell. It is soluble in many organic solvents such as methanol, ethanol and dichloromethane. It is relatively stable in air, but will decompose when heated or exposed to light.
Use:
1-(6-methoxypyridin-2-yl)ethanone is commonly used as an intermediate in organic synthesis. It can be used to synthesize compounds with biological activity, such as drugs, pesticides and dyes. In addition, it can also be used for application research in the field of organic optoelectronic devices.
Method:
The synthesis method of 1-(6-methoxypyridin-2-yl)ethanone can be obtained by the reaction of pyridine and acetic anhydride. First, pyridine is reacted with an excess of acetic anhydride in a solvent to produce 2-acetylpyridine. Then, 2-acetylpyridine is reacted with methanol to obtain 1-(6-methypyridin-2-yl) ethanone. The reaction is generally carried out at room temperature and usually requires the presence of a catalyst.
Safety Information:
1-(6-methoxypyridin-2-yl)ethanone is generally relatively safe under correct use and storage. However, it is still an organic compound, so appropriate safety measures need to be taken. Wear appropriate protective gloves, goggles, and protective clothing when handling the compound. Avoid inhaling its dust or contact with skin. If contact occurs, rinse immediately with plenty of water. In addition, the compound should be stored in a dry, well-ventilated place, away from combustibles and oxidants. Specific recommendations for safe handling and storage should refer to the relevant safety data sheet for the chemical.
Last Update：2024-04-09 21:01:54
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View History
2-Acetyl-6-methoxypyridine
2-Methyl-2-propanyl [(2S)-2-amino-2-phenylethyl]carbamate
6-Hydroxyhexan-6-olide
3-CHLORO-1,1-DIETHOXYPROPANE
Benz[d]indeno[4,5-b]pyran (8CI,9CI)
3-Amino-2-fluorotoluene, 2-Fluoro-m-toluidine
5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI)
subericaciddinitrile
3-Pyrrolidinecarboxylic acid, 1-methyl-, 1,1-dimethylethyl ester
L(+)-2,3-Diaminopropionic acid hydrochloride
2-Methyl-2-propanyl [(2S)-2-amino-2-phenylethyl]carbamate
6-Hydroxyhexan-6-olide
3-CHLORO-1,1-DIETHOXYPROPANE
Benz[d]indeno[4,5-b]pyran (8CI,9CI)
3-Amino-2-fluorotoluene, 2-Fluoro-m-toluidine
5-Pyrimidinecarboxylic acid, 2-amino-4-hydroxy-6-methyl- (6CI,8CI)
subericaciddinitrile
3-Pyrrolidinecarboxylic acid, 1-methyl-, 1,1-dimethylethyl ester
L(+)-2,3-Diaminopropionic acid hydrochloride