2-Acetyl-7-hydroxybenzofurane
2-Acetyl-7-hydroxybenzofuran
CAS: 40020-87-9
Molecular Formula: C10H8O3
2-Acetyl-7-hydroxybenzofurane - Names and Identifiers
| Name | 2-Acetyl-7-hydroxybenzofuran |
| Synonyms | 2-Acetylbenzofuran-7-ol 2-ACETYL-7-HYDROXYCOUMARONE 2-Acetyl-7-hydroxybenzofuran 2-ACETYL-7-HYDROXYBENZOFURAN 2-Acetyl-7-hydroxybenzofurane 1-(7-hydroxybenzofuran-2-yl)ethanone 1-(7-hydroxy-1-benzofuran-2-yl)ethanone 1-(7-Hydroxybenzofuran-2-yl)ethan-1-one 1-(7-Hydroxy-1-benzofuran-2-yl)ethanone |
| CAS | 40020-87-9 |
| InChI | InChI=1/C10H8O3/c1-6(11)9-5-7-3-2-4-8(12)10(7)13-9/h2-5,12H,1H3 |
2-Acetyl-7-hydroxybenzofurane - Physico-chemical Properties
| Molecular Formula | C10H8O3 |
| Molar Mass | 176.17 |
| Density | 1.292g/cm3 |
| Melting Point | 166°C |
| Boling Point | 327.8°C at 760 mmHg |
| Flash Point | 152°C |
| Vapor Presure | 0.000103mmHg at 25°C |
| Appearance | powder to crystal |
| Color | Light yellow to Yellow to Orange |
| Storage Condition | Room Temprature |
| Refractive Index | 1.626 |
| MDL | MFCD00191373 |
2-Acetyl-7-hydroxybenzofurane - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
2-Acetyl-7-hydroxybenzofurane - Introduction
It is an organic compound that contains a benzofuran ring and acetyl and hydroxyl substituents in its chemical structure.
Its properties are as follows:
Appearance: yellow to orange-yellow crystalline powder substance;
Melting point: about 116-120 degrees Celsius;
Solubility: can be dissolved in ethanol, methanol and ether and other organic solvents.
It is mainly used in organic synthesis reactions, for example, it can be used to synthesize other organic compounds, and it can also be used as a raw material for dyes and fluorescent probes. In addition, it also has anti-inflammatory, antibacterial, antioxidant and other biological activities, so it also has certain applications in the field of medicine.
The preparation method can be achieved by the following steps:
1. p-hydroxybenzoic acid and ethyl acetate are heated to reflux under acidic conditions to generate ethyl 2-acetyl benzoate.
2. The 2-acetyl benzoic acid ethyl ester is reacted with ethanol and a small amount of sulfuric acid to generate calcium.
In the use of phenanthrene need to pay attention to its safety:
1. The substance may be irritating to the eyes, skin and respiratory system, and should be rinsed with plenty of water immediately after contact.
2. use to avoid dust, to prevent inhalation and throat.
3. storage should be closed storage, avoid contact with the oxidant.
4. During use, follow correct operating procedures and wear appropriate protective equipment, such as gloves, goggles and protective masks.
Its properties are as follows:
Appearance: yellow to orange-yellow crystalline powder substance;
Melting point: about 116-120 degrees Celsius;
Solubility: can be dissolved in ethanol, methanol and ether and other organic solvents.
It is mainly used in organic synthesis reactions, for example, it can be used to synthesize other organic compounds, and it can also be used as a raw material for dyes and fluorescent probes. In addition, it also has anti-inflammatory, antibacterial, antioxidant and other biological activities, so it also has certain applications in the field of medicine.
The preparation method can be achieved by the following steps:
1. p-hydroxybenzoic acid and ethyl acetate are heated to reflux under acidic conditions to generate ethyl 2-acetyl benzoate.
2. The 2-acetyl benzoic acid ethyl ester is reacted with ethanol and a small amount of sulfuric acid to generate calcium.
In the use of phenanthrene need to pay attention to its safety:
1. The substance may be irritating to the eyes, skin and respiratory system, and should be rinsed with plenty of water immediately after contact.
2. use to avoid dust, to prevent inhalation and throat.
3. storage should be closed storage, avoid contact with the oxidant.
4. During use, follow correct operating procedures and wear appropriate protective equipment, such as gloves, goggles and protective masks.
Last Update：2024-04-09 19:05:49
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CAS: 40020-87-9
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CAS: 40020-87-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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