2-Amino-4,5-dimethoxybenzonitrile

2-Amino-4,5-dimethoxybenzonitrile - Names and Identifiers

Name	2-Amino-4,5-dimethoxybenzonitrile
Synonyms	TIMTEC-BB SBB002931 6-AMINOVERATRONITRILE LABOTEST-BB LT00080710 4-amino-5-cyanoveratrole 2-cyano-4,5-dimethoxyaniline 2-Amino-4,5-dimethoxybenzonitrile 2-AMINO-4,5-DIMETHOXYBENZONITRILE 2-amino-4,5-dimethoxy benzonitrile Benzonitrile, 2-amino-4,5-dimethoxy- 2-Cyano-4,5-dimethoxyaniline, 4,5-Dimethoxyanthranilonitrile, 6-Aminoveratronitrile
CAS	26961-27-3
InChI	InChI=1/C9H10N2O2/c1-12-8-3-6(5-10)7(11)4-9(8)13-2/h3-4H,11H2,1-2H3

2-Amino-4,5-dimethoxybenzonitrile - Physico-chemical Properties

Molecular Formula	C9H10N2O2
Molar Mass	178.19
Density	1.20±0.1 g/cm3(Predicted)
Melting Point	96-101°C(lit.)
Boling Point	346.6±42.0 °C(Predicted)
Flash Point	163.4°C
Vapor Presure	5.7E-05mmHg at 25°C
Appearance	Solid
BRN	2372149
pKa	1.99±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.555
MDL	MFCD00058682

2-Amino-4,5-dimethoxybenzonitrile - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	3276
WGK Germany	3
Hazard Note	Irritant
Hazard Class	6.1
Packing Group	III

2-Amino-4,5-dimethoxybenzonitrile - Introduction

2-Amino-4,5-dimethoxybenzonitrile is an organic compound with the chemical formula C10H12N2O2. It is a pale yellow crystalline solid, soluble in many organic solvents, such as ethanol, chloroform and dimethylformamide.

2-Amino-4,5-dimethoxybenzonitrile has many uses. First, it is widely used as an intermediate in the synthesis of other compounds, especially in the preparation of many heterocyclic compounds and drugs. Secondly, it can also be used for carbon-nitrogen bond formation reactions in organic synthesis, such as reacting with acylating reagents to obtain nitrile compounds. In addition, it can also be used as a precursor for dyes and pigments.

The method for preparing 2-Amino-4,5-dimethoxybenzonitrile is usually obtained by reacting 2-bromo-4, 5-dimethoxybenzonitrile with ammonia. First, 2-bromo-4, 5-dimethoxybenzonitrile is reacted with an excess of ammonia solution, typically at room temperature. After completion of the reaction, the resulting product can be purified by crystallization or column chromatography.

Regarding safety information, 2-Amino-4,5-dimethoxybenzonitrile should be handled with caution in chemical laboratories. It may cause irritation to the skin, eyes and respiratory tract, so appropriate personal protective equipment such as lab gloves, goggles and protective face masks should be worn during operation. In addition, it should be operated in a well-ventilated environment to avoid inhalation of gas or dust. Contact with oxidizing agents, strong acids and strong bases should be avoided during handling and storage. If necessary, refer to the Safety Data Form for chemicals for more detailed safety information.

Last Update：2024-04-09 21:01:54