2-Amino-5-Trifluoromethylbenzamide

2-Amino-5-Trifluoromethylbenzamide - Names and Identifiers

Name	2-Amino-5-Trifluoromethylbenzamide
Synonyms	2-AMino-5-trifluoroMethylbenzaMide 2-Amino-5-Trifluoromethylbenzamide Benzamide, 2-amino-5-(trifluoromethyl)-
CAS	16499-54-0

2-Amino-5-Trifluoromethylbenzamide - Physico-chemical Properties

Molecular Formula	C8H7F3N2O
Molar Mass	204.15
Density	1.418±0.06 g/cm3(Predicted)
Boling Point	258.3±40.0 °C(Predicted)
pKa	15.08±0.50(Predicted)

2-Amino-5-Trifluoromethylbenzamide - Introduction

It is an organic compound with the chemical formula C8H6F3N2O. It has the following properties:

1. Appearance: It is a white crystalline solid.
2. Solubility: It is soluble in ethanol, chloroform and dimethyl thiourea, slightly soluble in water.
3. Melting Point: the melting point of is about 118-120 ℃.
4. Molecular Weight: its relative molecular mass is 214.14.

It is mainly used in the field of organic synthesis. It can be used as an important intermediate for the preparation of other compounds, such as drugs and dyes. In the field of medicine, it has certain application value in the synthesis of anti-cancer drugs and antiviral drugs.

The method of preparing the sodium chloride includes the reaction of benzoyl chloride (C6H5C(O)Cl) and 2-amino -5-trifluoromethylaniline (C7H7NF3). The reaction process often requires the presence of an organic solvent and a catalyst.

Regarding safety information, irritant to skin, eyes and respiratory tract. In the use of need to pay attention to protective measures, avoid contact with the skin and eyes, if necessary, should wear protective glasses and gloves. At the same time, it should be operated in a well-ventilated place, and the hands and other exposed parts should be cleaned in time after treatment. In case of accidental contact or accidental ingestion, seek medical attention or professional help.

Last Update：2024-04-09 21:11:58