2-Amino-5-bromo-3-iodopyridine
2-Amino-5-bromo-3-iodopyridine
CAS: 381233-96-1
Molecular Formula: C5H4BrIN2
2-Amino-5-bromo-3-iodopyridine - Names and Identifiers
| Name | 2-Amino-5-bromo-3-iodopyridine |
| Synonyms | 5-Bromo-3-iodopyridin-2-amine 5-Bromo-3-iodo-2-pyridinamine 2-Amine-5-bromo-3-iodopyridine 2-Amino-5-bromo-3-iodopyridine 2-AMINO-5-BROMO-3-IODOPYRIDINE 2-Amino-3-iodo-5-bromopyridine 2-PyridinaMine,5-broMo-3-iodo- 5-BROMO-3-IODO-PYRIDIN-2-YLAMINE |
| CAS | 381233-96-1 |
| InChI | InChI=1/C5H4BrIN2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9) |
| InChIKey | XPERZSKJGNUSHI-UHFFFAOYSA-N |
2-Amino-5-bromo-3-iodopyridine - Physico-chemical Properties
| Molecular Formula | C5H4BrIN2 |
| Molar Mass | 298.91 |
| Density | 2.426±0.06 g/cm3(Predicted) |
| Melting Point | 111-112°C |
| Boling Point | 308.2±42.0 °C(Predicted) |
| Flash Point | 140.2°C |
| Vapor Presure | 0.000691mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Yellow to Orange |
| pKa | 2.25±0.49(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Light Sensitive |
| Refractive Index | 1.73 |
| MDL | MFCD06659000 |
2-Amino-5-bromo-3-iodopyridine - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36:37/38 - R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37 - Wear suitable gloves. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT, LIGHT SENS |
2-Amino-5-bromo-3-iodopyridine - Introduction
It is an organic compound with the chemical formula C5H3BrIN2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a solid in the form of white crystals or crystalline powder.
-Solubility: It can be dissolved in some organic solvents, such as ethanol and dimethyl sulfite, but its solubility in water is low.
-Melting point: Its melting point is about 145-148°C.
-Stability: It is relatively stable at room temperature, but decomposition reaction may occur when encountering light or high temperature.
Use:
-or can be used as reagents and intermediates in organic synthesis. It can be used to synthesize various nitrogen-containing organic compounds, such as pyridine derivatives and biologically active compounds.
-In the field of medicine, it may be used to synthesize new drug molecules or study the mechanism of drug action.
Preparation Method:
The preparation method of the salt is more complicated and is usually obtained through multi-step synthesis. One of the synthetic methods includes bromination and iodination of pyridine using bromine and iodine, followed by reduction or strong alkali treatment of the product using imine or hydrogen amino groups, and finally the target product is obtained.
Safety Information:
-It may be harmful to the human body, and direct contact with skin, eyes and respiratory tract should be avoided. Wear appropriate personal protective equipment, such as gloves, safety glasses and protective masks.
-During use or storage, keep away from combustibles and strong oxidants to avoid fire or explosion caused by reaction with these substances.
-In the event of a leak or accident, appropriate emergency measures such as ventilation, removal of leaks and use of protective equipment are required. If necessary, seek medical assistance quickly.
In general, it is a reagent and intermediate commonly used in organic synthesis for the preparation of nitrogen-containing organic compounds. During use, it is necessary to pay attention to safe operation and follow relevant laboratory safety regulations and guidelines.
Nature:
-Appearance: It is a solid in the form of white crystals or crystalline powder.
-Solubility: It can be dissolved in some organic solvents, such as ethanol and dimethyl sulfite, but its solubility in water is low.
-Melting point: Its melting point is about 145-148°C.
-Stability: It is relatively stable at room temperature, but decomposition reaction may occur when encountering light or high temperature.
Use:
-or can be used as reagents and intermediates in organic synthesis. It can be used to synthesize various nitrogen-containing organic compounds, such as pyridine derivatives and biologically active compounds.
-In the field of medicine, it may be used to synthesize new drug molecules or study the mechanism of drug action.
Preparation Method:
The preparation method of the salt is more complicated and is usually obtained through multi-step synthesis. One of the synthetic methods includes bromination and iodination of pyridine using bromine and iodine, followed by reduction or strong alkali treatment of the product using imine or hydrogen amino groups, and finally the target product is obtained.
Safety Information:
-It may be harmful to the human body, and direct contact with skin, eyes and respiratory tract should be avoided. Wear appropriate personal protective equipment, such as gloves, safety glasses and protective masks.
-During use or storage, keep away from combustibles and strong oxidants to avoid fire or explosion caused by reaction with these substances.
-In the event of a leak or accident, appropriate emergency measures such as ventilation, removal of leaks and use of protective equipment are required. If necessary, seek medical assistance quickly.
In general, it is a reagent and intermediate commonly used in organic synthesis for the preparation of nitrogen-containing organic compounds. During use, it is necessary to pay attention to safe operation and follow relevant laboratory safety regulations and guidelines.
Last Update：2024-04-09 19:05:49
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QQ: 3008007409
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