2-Amino-5-carboxy-1,3-thiazole

2-Amino-5-carboxy-1,3-thiazole - Names and Identifiers

Name	2-Amino-1,3-thiazole-5-carboxylic Acid
Synonyms	RARECHEM AL BE 1263 2-aminothiazole-5-formic acid 2-Amino-5-carboxy-1,3-thiazole 2-AMINO-5-THIAZOLECARBOXYLIC ACID 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID 2-Aminothiazole-5-Carboxylic Acid 2-AMINOTHIAZOL-5-YLCARBOXYLIC ACID 5-Thiazolecarboxylic acid, 2-aMino- 5-Thiazolecarboxylic acid, 2-amino- 2-Amino-1,3-thiazole-5-carboxylic acid 2-Amino-1,3-thiazole-5-carboxylic Acid
CAS	40283-46-3
EINECS	609-810-4
InChI	InChI=1/C4H4N2O2S/c5-4-6-1-2(9-4)3(7)8/h1H,(H2,5,6)(H,7,8)

2-Amino-5-carboxy-1,3-thiazole - Physico-chemical Properties

Molecular Formula	C4H4N2O2S
Molar Mass	144.15
Density	1.657±0.06 g/cm3(Predicted)
Melting Point	214-216
Boling Point	415.0±18.0 °C(Predicted)
Flash Point	204.8°C
Vapor Presure	1.25E-07mmHg at 25°C
Appearance	Crystalline Powder
Color	Off-white to yellow
pKa	2.14±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	1.707
MDL	MFCD06203554

2-Amino-5-carboxy-1,3-thiazole - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	36/37 - Wear suitable protective clothing and gloves.
HS Code	29341000
Hazard Note	Irritant/Keep Cold

2-Amino-5-carboxy-1,3-thiazole - Introduction

2-Amino-1, 3-thiazole-5-carbostylic Acid(2-Amino-1, 3-thiazole-5-carbostylic Acid) is an organic compound whose chemical formula is C4H4N2O2S.

Nature:
2-Amino-1,3-thiazole-5-carboxylic Acid is a colorless or pale yellow solid, sometimes in powder form. It is stable at room temperature and pressure, but can be decomposed at high temperatures. It is soluble in water and many organic solvents, such as ethanol, acetone and dimethyl sulfoxide.

Use:
2-Amino-1,3-thiazole-5-carboxylic Acid is one of the important intermediates in the synthesis of natural products and drug molecules. It can be used to synthesize various compounds containing thiazole structure, such as drugs, pesticides and dyes. In addition, 2-Amino-1,3-thiazole-5-carboxylic Acid can also be used as a ligand for metal ions and polymers.

Preparation Method:
2-Amino-1, 3-thiazole-5-carbylic Acid has many synthesis methods. One of the commonly used methods is to conduct a condensation reaction between hydroxyacetonitrile and thioacetate, and then carry out acid hydrolysis to obtain the target product.

Safety Information:
2-Amino-1, 3-thiazole-5-carbolic Acid is generally considered to be a low-toxic compound, but it is still necessary to comply with general laboratory safety procedures. Contact with skin, eyes, inhalation or ingestion may cause irritation and direct contact should be avoided. Wear appropriate protective equipment such as gloves and goggles when used. Avoid contact with oxidizing agents and high temperatures during storage and handling. In the event of an accident, medical help should be sought immediately.

Last Update：2024-04-09 20:52:54