2-Amino-5-chloro-3-iodopyridine

2-Amino-5-chloro-3-iodopyridine - Names and Identifiers

Name	2-Amino-5-chloro-3-iodopyridine
Synonyms	5-chloro-3-iodo-2-pyridinamine 5-Chloro-3-iodopyridin-2-amine 5-chloro-3-iodopyridin-2-amine 2-amino-3-iodo-5-chloropyridine 2-AMINO-5-CHLORO-3-IODOPYRIDINE 2-AMINO-5-CHLORO-4-IODOPYRIDINE 2-Amino-5-chloro-3-iodopyridine 2-PyridinaMine, 5-chloro-3-iodo- 5-CHLORO-3-IODO-PYRIDIN-2-YLAMINE
CAS	211308-81-5
InChI	InChI=1/C5H4ClIN2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9)

2-Amino-5-chloro-3-iodopyridine - Physico-chemical Properties

Molecular Formula	C5H4ClIN2
Molar Mass	254.46
Density	2.139±0.06 g/cm3(Predicted)
Melting Point	137-138°C
Boling Point	306.9±42.0 °C(Predicted)
Flash Point	139.41°C
Vapor Presure	0.001mmHg at 25°C
Appearance	Yellow
pKa	2.27±0.49(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Light Sensitive
Refractive Index	1.708
MDL	MFCD07644578

2-Amino-5-chloro-3-iodopyridine - Risk and Safety

Risk Codes	22 - Harmful if swallowed
Hazard Class	IRRITANT
Packing Group	III

2-Amino-5-chloro-3-iodopyridine - Reference Information

Uses

2-amino-5-chloro-3-iodopyridine and its derivatives are a very useful class of aminopyridine derivatives. As an important pharmaceutical intermediate, it can be used to synthesize drugs for the treatment of digestive system diseases-pirenzepine. Pirenzepine is an excellent anti-ulcer drug, mainly used for the treatment of gastric and duodenal ulcers. Aminopyridine is used to synthesize anti-peptic ulcer drug pirenzepine, can also be used to synthesize diazepine anti-AIDS drugs, and can be used as a drug intermediate for pesticides. 2-Amino-5-chloro-3-iodopyridine is a useful synthetic intermediate. Rational design for highly selective tyrosine kinase inhibitors. It is also used to synthesize azaindole derivatives with antibacterial and antifungal activities. Therefore, the research on the synthesis of 2-amino -5-chloro -3-iodopyridine is of great significance and has a very broad prospect.

Last Update：2024-04-09 20:52:54