2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide
CAS: 20878-51-7
Molecular Formula: C16H18N2O4
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide - Names and Identifiers
| Name | 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide |
| Synonyms | 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide Benzamide, 2-amino-N-(3,4,5-trimethoxyphenyl)- |
| CAS | 20878-51-7 |
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide - Physico-chemical Properties
| Molecular Formula | C16H18N2O4 |
| Molar Mass | 302.33 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD10021566 |
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide - Risk and Safety
| Hazard Class | IRRITANT |
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide - Introduction
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide, the chemical formula is C16H18N2O4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White or light yellow crystalline powder.
-Melting point: about 172-174°C.
-Solubility: Soluble in acid, alkali and organic solvents, insoluble in water.
Use:
- 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide is a pharmaceutical intermediate that can be used to synthesize other compounds or drugs.
-It is also used as a reaction reagent in organic synthesis.
Preparation Method:
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide can be prepared as follows:
1. First, terephthalamide was prepared. Hydroquinone is heated with excess phenol under the catalysis of sulfuric acid to form terephthalamide.
2. Then, under alkaline conditions, the terephthalamide is reacted with p-phenylenediamine to obtain 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide.
Safety Information:
- 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide should be used and stored in accordance with general laboratory safety measures.
-It may be irritating to the eyes, skin and respiratory tract, so it is recommended to wear appropriate protective equipment during operation.
-Rinse with plenty of water immediately after contact and seek medical assistance if necessary.
Nature:
-Appearance: White or light yellow crystalline powder.
-Melting point: about 172-174°C.
-Solubility: Soluble in acid, alkali and organic solvents, insoluble in water.
Use:
- 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide is a pharmaceutical intermediate that can be used to synthesize other compounds or drugs.
-It is also used as a reaction reagent in organic synthesis.
Preparation Method:
2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide can be prepared as follows:
1. First, terephthalamide was prepared. Hydroquinone is heated with excess phenol under the catalysis of sulfuric acid to form terephthalamide.
2. Then, under alkaline conditions, the terephthalamide is reacted with p-phenylenediamine to obtain 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide.
Safety Information:
- 2-Amino-N-(3,4,5-trimethoxyphenyl)benzamide should be used and stored in accordance with general laboratory safety measures.
-It may be irritating to the eyes, skin and respiratory tract, so it is recommended to wear appropriate protective equipment during operation.
-Rinse with plenty of water immediately after contact and seek medical assistance if necessary.
Last Update：2024-04-09 21:01:54
