2-Amino-pyrimidine-4-carboxylicacid

2-Amino-pyrimidine-4-carboxylicacid - Names and Identifiers

Name	2-Aminopyrimidine-4-carboxylic acid
Synonyms	H-2APY4-OH 4-pyrimidinecarboxylicacid 4-Carboxypyrimidin-2-amine 2-Aminopyrimidine-4-carboxylic acid 2-Amino-pyrimidine-4-carboxylicacid 2-Amino-Pyrimidine-4-Carboxylic Acid 2-AMINO-PYRIMIDINE-4-CARBOXYLIC ACID 2-azanylpyrimidine-4-carboxylic acid 4-Pyrimidinecarboxylic acid, 2-amino- 4-Pyrimidinecarboxylic acid, 2-amino- (7CI,8CI,9CI) 2-Amino-4-carboxypyrimidine, 2-Amino-4-carboxy-1,3-diazine
CAS	2164-65-0
InChI	InChI=1/C5H5N3O2/c6-5-7-2-1-3(8-5)4(9)10/h1-2H,(H,9,10)(H2,6,7,8)

2-Amino-pyrimidine-4-carboxylicacid - Physico-chemical Properties

Molecular Formula	C5H5N3O2
Molar Mass	139.11
Density	1.533±0.06 g/cm3(Predicted)
Melting Point	285 °C
Boling Point	474.6±37.0 °C(Predicted)
Flash Point	240.8°C
Vapor Presure	8.19E-10mmHg at 25°C
pKa	1.55±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.663

2-Amino-pyrimidine-4-carboxylicacid - Risk and Safety

Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves.
HS Code	29335990

2-Amino-pyrimidine-4-carboxylicacid - Introduction

Nature:
-Appearance: white crystal or powder
-Molecular weight: 139.11g/mol
-Melting Point: 234-237 ℃
-Solubility: Soluble in water and ethanol
- pH: Neutral

Use:
-fluoric acid is often used as an intermediate in the pharmaceutical field for the synthesis of pyrimidine compounds, such as anti-cancer drugs.
-It can also be used as a catalyst to participate in catalytic reactions.
-In addition, it is also used in organic synthesis, functional materials, pesticides and dyes.

Method:
The preparation method of acid can be carried out by the following steps:
1. Dissolve 2-aminopyrimidine in sodium hydroxide solution.
2. Add chloroacetic acid to react to generate 2-aminopyrimidine -4-acetic acid.
3. Esterification or hydrolysis of 2-aminopyrimidine -4-acetic acid is carried out to finally obtain acid.

Safety Information:
-the acid in contact with skin, eyes or inhalation may be harmful to health, should pay attention to protective measures.
-Use should wear appropriate protective gloves and mask, maintain good ventilation.
-Avoid contact with strong oxidants and other substances to prevent dangerous reactions.
-If accidental contact or inhalation, rinse immediately with plenty of water and seek medical help.
-Storage should be protected from moisture, away from fire and high temperature, and keep airtight.

Please note that the information provided here is for reference only. The specific operation and use should be carried out in accordance with the standard operating procedures of chemical experiments and relevant laws and regulations.

Last Update：2024-04-09 20:52:54

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