2-Aminobenzenesulfonamide
2-Aminobenzenesulfonamide
CAS: 3306-62-5
Molecular Formula: C6H8N2O2S
2-Aminobenzenesulfonamide - Names and Identifiers
| Name | 2-Aminobenzenesulfonamide |
| Synonyms | 2-Sulphamoylaniline 2-Aminobenzenesulfamide 2-Aminobenzenesulfonamde 2-Amino-benzenesulfomide 2-amino-benzenesulfonamid 2-Aminobenzenesulfonamide 2-Aminophenyl sulfonyl Chloride Benzenesulfonamide, 2-amino- (9CI) |
| CAS | 3306-62-5 |
| EINECS | 221-988-1 |
| InChI | InChI=1/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) |
| InChIKey | YAZSBRQTAHVVGE-UHFFFAOYSA-N |
2-Aminobenzenesulfonamide - Physico-chemical Properties
| Molecular Formula | C6H8N2O2S |
| Molar Mass | 172.2 |
| Density | 1.3250 (rough estimate) |
| Melting Point | 155-157°C(lit.) |
| Boling Point | 392.7±44.0 °C(Predicted) |
| Flash Point | 191.3°C |
| Water Solubility | 6.655g/L(24 ºC) |
| Solubility | DMSO (Sparingly), Methanol (Slightly) |
| Vapor Presure | 2.25E-06mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | Off-White to Beige |
| pKa | 10.29±0.60(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.6490 (estimate) |
| MDL | MFCD00007932 |
| Physical and Chemical Properties | Crystals of platelets or prisms. Melting point 152-153 °c. Soluble in ethanol, acetic acid. |
| Use | Used as pharmaceutical and dye intermediates |
2-Aminobenzenesulfonamide - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | DA9449000 |
| HS Code | 29350090 |
| Hazard Note | Irritant |
2-Aminobenzenesulfonamide - Reference Information
| Biological activity | 2-Aminobenzenesulfonamide is an inhibitor of carbonic anhydrase IX (carbonic anhydrase IX). |
| target | carbonic anhydrase IX |
| uses | pharmaceutical intermediates for the production of antihypertensive azines. Used as an intermediate in medicine and dyes |
| production method | o-nitrobenzenesulfonamide is reduced. Put o-nitrobenzenesulfonamide, hot water, and acetic acid into the reaction tank, and stir and heat until boiling. Add the iron filings in 6 times, each half an hour apart. When iron filings are added, the reaction liquid remains boiling. After adding iron filings, continue boiling for 3 hours. Filter while hot, and then boil the filter residue with hot water and filter it. The filtrates were combined twice and cooled to crystallize overnight. Filtration, drying, and o-aminobenzene sulfonamide. |
Last Update：2024-04-09 20:49:11
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Product Name: 2-Aminobenzenesulfonamide Visit Supplier Webpage Request for quotationCAS: 3306-62-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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