2-Aminothiazole-5-carbaldehyde

2-Aminothiazole-5-carbaldehyde - Names and Identifiers

Name	2-Amino-5-formylthiazole
Synonyms	2-AMINO-5-FORMYLTHIAZOLE 2-Amino-5-formylthiazole 2-Amino-5-formyl-1,3-thiazole 2-Aminothiazole-5-carbadehyde 2-AMINOTHIAZOLE-5-CARBALDEHYDE 2-AMINOTHIAZOLE-5-CARBOXALDEHYDE 2-amino-1,3-thiazole-5-carbaldehyde
CAS	1003-61-8
InChI	InChI=1/C4H4N2OS/c5-4-6-1-3(2-7)8-4/h1-2H,(H2,5,6)
InChIKey	HZKMBJCDAXLMDN-UHFFFAOYSA-N

2-Aminothiazole-5-carbaldehyde - Physico-chemical Properties

Molecular Formula	C4H4N2OS
Molar Mass	128.15
Density	1.488±0.06 g/cm3(Predicted)
Melting Point	122-132°C
Boling Point	316.3±15.0 °C(Predicted)
Flash Point	145.1°C
Vapor Presure	0.000413mmHg at 25°C
pKa	3.16±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Sensitive	Air Sensitive
Refractive Index	1.712
MDL	MFCD02179570
Physical and Chemical Properties	Storage Conditions: Keep Cold sensitivity: Air Sensitive WGK Germany:3

2-Aminothiazole-5-carbaldehyde - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3
HS Code	29349990
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

2-Aminothiazole-5-carbaldehyde - Introduction

2-Amino-5-formylthiazole (2-Amino-5-formylthiazole) is an organic compound with the chemical formula C4H4N2OS.

Nature:
- 2-Amino -5-aldehyde thiazole is a colorless to slightly yellow crystalline or powdery solid.
-It is slightly soluble in water and soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-The compound is weakly acidic.

Use:
- 2-amino -5-aldehyde thiazole is widely used in organic synthesis as a synthetic intermediate.
-It can be used to synthesize other compounds, such as organic fluorescent dyes, biologically active molecules, etc.
-It can also be used as a ligand in coordination chemistry to participate in metal ion coordination reactions.

Preparation Method:
The preparation method of -2-amino -5-aldehyde thiazole is mainly obtained by N-deprotection or N-defunctional reaction of thiazole.
-A commonly used synthesis method is to react thiazole with N-methyl-N-nitroglycine ester, and deprotection under appropriate conditions to obtain 2-amino-5-aldehydyl thiazole.

Safety Information:
- 2-amino -5-aldehyde thiazole compounds are less toxic and corrosive to human body.
-During operation and storage, avoid contact with harmful substances such as strong oxidants and strong acids.
-When using this compound, wear protective gloves and protective glasses to avoid inhaling its dust or touching your skin.
-In case of accidental contact or inhalation, flush with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15