| Molecular Formula | C2HBrClF3 |
| Molar Mass | 197.38 |
| Density | 1.872 g/mL at 25 °C(lit.) |
| Melting Point | -115.75°C |
| Boling Point | 50.2 °C(lit.) |
| Flash Point | 49-50°C |
| Water Solubility | Soluble in water (8 mg/ml). |
| Vapor Presure | 4.5 psi ( 20 °C) |
| Appearance | Morphological Colorless liquid |
| Storage Condition | 2-8°C |
| Stability | Light Sensitive |
| Refractive Index | n20/D 1.369(lit.) |
| Physical and Chemical Properties | Chemical properties colorless transparent and easy-to-flow volatile liquid. Boiling point 50.2 ℃, relative density 1.86(20/4 ℃), refractive index 1.3691. It is miscible with organic solvents and slightly soluble in water. It has unpleasant fragrance, sweet taste and burning feeling. Stable nature, no combustion explosion. |
| Use | This product is a commonly used new type of general inhalation anesthetics. The anesthetic effect is stronger and faster than ether, the induction period is very short, but the analgesic and muscle relaxation effect is not strong, the dosage is small, no stimulation. Can be used for minor surgery or combined anesthesia. The disadvantage of the product is the inhibition of the heart and the expansion of blood vessels, can make blood pressure drop, cerebral vascular expansion lead to increased intracranial pressure and the respiratory center has inhibitory effect. |
| Risk Codes | R61 - May cause harm to the unborn child R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R40 - Limited evidence of a carcinogenic effect R20 - Harmful by inhalation |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. |
| UN IDs | UN 3334 |
| WGK Germany | 3 |
| RTECS | KH6550000 |
| FLUKA BRAND F CODES | 8-19 |
| HS Code | 2937990000 |
| Toxicity | LD50 oral in rat: 5680mg/kg |
| toxic substance data | 151-67-7(Hazardous Substances Data) |
| solubility | Slightly soluble in water, miscible with anhydrous ethanol and with trichloroethylene. |
| Merck | 14,4603 |
| BRN | 1736947 |
| exposure limit | TLV-TWA 50 ppm (~400 mg/m3) (ACGIH). |
| EPA chemical information | Halothane (151-67-7) |
biological activity
Halothane (Narcotane) is an inhalation anesthetic used for the induction and maintenance of general anesthesia.
production method
It is prepared from trifluorotrichloroethane through elimination, addition, rearrangement, reduction and other steps.