2-BROMO-5-FLUORO-3-NITROPYRIDINE

2-BROMO-5-FLUORO-3-NITROPYRIDINE - Names and Identifiers

Name	2-bromo-5-fluoro-3-nitropyridine
Synonyms	LogP 2-BROMO-5-FLUORO-3-NITROPYRDINE 2-Bromo-5-fluoro-2-nitropyrdine 2-BROMO-5-FLUORO-3-NITROPYRIDINE 2-bromo-5-fluoro-3-nitropyridine Pyridine, 2-bromo-5-fluoro-3-nitro- pyridine, 2-bromo-5-fluoro-3-nitro-
CAS	652160-72-0
InChI	InChI=1/C5H2BrFN2O2/c6-5-4(9(10)11)1-3(7)2-8-5/h1-2H

2-BROMO-5-FLUORO-3-NITROPYRIDINE - Physico-chemical Properties

Molecular Formula	C5H2BrFN2O2
Molar Mass	220.98
Density	1.923
Boling Point	227℃
Flash Point	91℃
Water Solubility	Slightly soluble in water.
Vapor Presure	0.118mmHg at 25°C
Appearance	Solid
Color	Pale orange
pKa	-5.67±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.586

2-BROMO-5-FLUORO-3-NITROPYRIDINE - Introduction

It is an organic compound with the chemical formula C5H2BrFN2O2. It is a yellow crystalline solid with a high melting and boiling point.

This compound has a wide range of applications in the chemical industry. It can be used as a raw material and intermediate in organic synthesis for the synthesis of other compounds. In medicinal chemistry, it has potential biological activity and may be used in the synthesis of novel drugs. In addition, it can also be applied in the manufacturing process of pesticides and dyes.

preparation can generally be obtained by the substitution reaction of pyridine. First, pyridine is reacted with a bromine atom to form 2-bromopyridine, which is then reacted with nitric acid and nitrous acid to form 2-bromo-3-nitropyridine. Finally, a fluorine atom is introduced into 2-bromo-3-nitropyridine by a fluorination reaction to obtain the final product.

Regarding safety information, is an organic compound with potential toxicity. During handling and use, relevant safety practices should be followed, including wearing protective gloves, eye protection and suitable ventilation equipment. At the same time, care should be taken to avoid contact with strong oxidants and combustibles, and to stay away from heat sources and open flames. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical attention.

Last Update：2024-04-09 21:11:58