2-BROMO-5-METHYL-PHENYLAMINE - Names and Identifiers
2-BROMO-5-METHYL-PHENYLAMINE - Physico-chemical Properties
Molecular Formula | C7H8BrN
|
Molar Mass | 186.05 |
Density | 1.486 g/mL at 25 °C |
Melting Point | 46°C |
Boling Point | 130°C/16mmHg(lit.) |
Flash Point | 110°C |
Vapor Presure | 0.0249mmHg at 25°C |
Appearance | White crystalline powder |
pKa | 2.66±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.603 |
MDL | MFCD01806278 |
2-BROMO-5-METHYL-PHENYLAMINE - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
|
Safety Description | S9 - Keep container in a well-ventilated place.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
S60 - This material and its container must be disposed of as hazardous waste.
|
UN IDs | 2811 |
WGK Germany | 3 |
HS Code | 29214300 |
Hazard Class | 6.1 |
2-BROMO-5-METHYL-PHENYLAMINE - Introduction
2-Bromo-5-methylbenzenamine, chemical formula C7H8NBr, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless to light yellow crystal
-Molecular weight: 186.05g/mol
-melting point: 75-77 ℃
-Boiling point: 260 ℃
-Solubility: Soluble in alcohols and organic solvents, slightly soluble in water
-Density: 1.342g/cm³
Use:
- 2-Bromo-5-methylbenzenamine can be used as starting material, intermediate and reagent in organic synthesis.
-Used in the synthesis of antibiotics and biologically active compounds in drug synthesis.
-Acts as an intermediate in the synthesis of certain pigments and dyes.
-Also used for the preparation of organometallic complexes and organic synthesis catalysts.
Preparation Method:
2-Bromo-5-methylbenzenamine can be obtained by reacting aniline with methyl bromide. The main steps of the reaction are as follows:
1. Dissolve aniline under acidic conditions.
2. slowly add methyl bromide dropwise and heat the reaction mixture.
3. Cool the reaction mixture to give the crystalline product.
4. The product was filtered, washed and dried to obtain pure 2-Bromo-5-methylbenzenamine.
Safety Information:
- 2-Bromo-5-methylbenzenamine is irritating and appropriate protective measures should be taken, such as wearing gloves and goggles.
-has a corrosive effect on the skin and eyes, should be washed with plenty of water immediately after contact, and medical treatment.
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-During storage and use, avoid contact with oxidants and strong acids to avoid dangerous reactions.
-Specific safety operation guidelines and handling methods should refer to the safety data sheet of the chemical.
Last Update:2024-04-09 02:00:46