2-BROMO-N-(1-PHENYL-ETHYL)-ACETAMIDE
2-bromo-N-(1-phenylethyl)acetamide
CAS: 70110-38-2
Molecular Formula: C10H12BrNO
2-BROMO-N-(1-PHENYL-ETHYL)-ACETAMIDE - Names and Identifiers
| Name | 2-bromo-N-(1-phenylethyl)acetamide |
| Synonyms | ALD-N013385 CHEMBRDG-BB 4023675 2-bromo-N-(1-phenylethyl)acetamide 2-bromo-N-(1-phenylethyl)ethanamide 2-BROMO-N-(1-PHENYL-ETHYL)-ACETAMIDE acetamide, 2-bromo-N-(1-phenylethyl)- |
| CAS | 70110-38-2 |
| InChI | InChI=1/C10H12BrNO/c1-8(12-10(13)7-11)9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,13) |
2-BROMO-N-(1-PHENYL-ETHYL)-ACETAMIDE - Physico-chemical Properties
| Molecular Formula | C10H12BrNO |
| Molar Mass | 242.11 |
| Density | 1.382g/cm3 |
| Boling Point | 373.345°C at 760 mmHg |
| Flash Point | 179.593°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| Refractive Index | 1.558 |
| MDL | MFCD05624926 |
2-BROMO-N-(1-PHENYL-ETHYL)-ACETAMIDE - Risk and Safety
| Hazard Class | IRRITANT |
2-BROMO-N-(1-PHENYL-ETHYL)-ACETAMIDE - Introduction
2-bromo-N-(1-phenylethyl)acetamide is an organic compound with the chemical formula C10H12BrNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-bromo-N-(1-phenylethyl) is acetamide a colorless or pale yellow crystalline solid.
-Solubility: It is soluble in organic solvents such as alcohols, ethers, ketones and esters.
-melting point: its melting point is between 60-62 ℃.
Use:
2-bromo-N-(1-phenylethyl)acetamide can be used as an organic synthesis intermediate and play an important role in drug synthesis and other organic chemical reactions.
Preparation Method:
The preparation of-2-bromo-N-(1-phenylethyl)acetamide can be achieved by bromination of acetamide, usually using ferrous bromide or other brominating agents, and the reaction conditions require heating.
-reaction equation: CH3CONH2 Br2 -> CH3CONHBr HBr
-Next, the resulting bromoacetamide can be reacted with 1-phenylethylammonium bromide to give the final product 2-bromo-N-(1-phenylethyl)acetamide.
-reaction equation: CH3CONHBr C6H5CH2CH2Br -> CH3CONHC6H5CH2CH2Br HBr
Safety Information:
- 2-bromo-N-(1-phenylethyl)acetamide is an organic bromine compound with certain risks.
-Take appropriate protective measures during handling and storage, such as wearing protective gloves, goggles and protective clothing.
-Avoid inhaling its vapors or dust, and avoid contact with skin and eyes.
-Please read and understand the safety data sheet carefully before use, and deal with it in accordance with the correct operating procedures.
Nature:
-Appearance: 2-bromo-N-(1-phenylethyl) is acetamide a colorless or pale yellow crystalline solid.
-Solubility: It is soluble in organic solvents such as alcohols, ethers, ketones and esters.
-melting point: its melting point is between 60-62 ℃.
Use:
2-bromo-N-(1-phenylethyl)acetamide can be used as an organic synthesis intermediate and play an important role in drug synthesis and other organic chemical reactions.
Preparation Method:
The preparation of-2-bromo-N-(1-phenylethyl)acetamide can be achieved by bromination of acetamide, usually using ferrous bromide or other brominating agents, and the reaction conditions require heating.
-reaction equation: CH3CONH2 Br2 -> CH3CONHBr HBr
-Next, the resulting bromoacetamide can be reacted with 1-phenylethylammonium bromide to give the final product 2-bromo-N-(1-phenylethyl)acetamide.
-reaction equation: CH3CONHBr C6H5CH2CH2Br -> CH3CONHC6H5CH2CH2Br HBr
Safety Information:
- 2-bromo-N-(1-phenylethyl)acetamide is an organic bromine compound with certain risks.
-Take appropriate protective measures during handling and storage, such as wearing protective gloves, goggles and protective clothing.
-Avoid inhaling its vapors or dust, and avoid contact with skin and eyes.
-Please read and understand the safety data sheet carefully before use, and deal with it in accordance with the correct operating procedures.
Last Update：2024-04-09 02:00:47
