2-BROMOPHENYLMORPHOLINE - Names and Identifiers
2-BROMOPHENYLMORPHOLINE - Physico-chemical Properties
Molecular Formula | C10H12BrNO
|
Molar Mass | 242.11 |
Density | 1.433±0.06 g/cm3(Predicted) |
Boling Point | 324.8±37.0 °C(Predicted) |
pKa | 4.47±0.40(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
2-BROMOPHENYLMORPHOLINE - Introduction
Morpholine, 4-(2-bromophenyl)-, also known as bromomorpholine, has the chemical formula C10H11BrNO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Morpholine, 4-(2-bromophenyl)-as a white crystalline solid.
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide.
-Melting point: about 69-73°C.
-Boiling point: about 290°C.
Use:
- Morpholine, 4-(2-bromophenyl)-can be used as an intermediate in organic synthesis.
-The compound may be used as a pharmaceutical raw material in the field of agrochemicals and pharmaceuticals.
Preparation Method:
Morpholine, 4-(2-bromophenyl)-can be prepared by the following steps:
1. take aniline (C6H5NH2) and cuprous bromide (CuBr) reaction, generate 2-bromoaniline (C6H5NH2Br).
2. reaction 2-bromoaniline reacts with morpholine (C4H9NO) to replace one hydrogen atom in morpholine through SNAr reaction to obtain Morpholine, 4-(2-bromophenyl)-.
Safety Information:
- Morpholine, 4-(2-bromophenyl)-is an organic bromide that is irritating to the eyes and skin.
-Avoid contact with skin and eyes during operation, and wear protective gloves and goggles.
-In case of contact with skin, rinse immediately with plenty of water and seek medical help.
-During use or storage, follow proper laboratory safety procedures to ensure storage in sealed containers.
Last Update:2024-04-09 15:18:00