2-Bromo-1-(4-methoxyphenyl)propan-1-one - Names and Identifiers
2-Bromo-1-(4-methoxyphenyl)propan-1-one - Physico-chemical Properties
Molecular Formula | C10H11BrO2
|
Molar Mass | 243.1 |
Density | 1.388g/cm3 |
Boling Point | 313.3°C at 760 mmHg |
Flash Point | 143.3°C |
Vapor Presure | 0.000502mmHg at 25°C |
Refractive Index | 1.544 |
2-Bromo-1-(4-methoxyphenyl)propan-1-one - Introduction
2-bromo-1-(4-methoxyphenyl)propan-1-one is an organic compound with the molecular formula C11H13BrO2. It is a white crystalline solid with a peculiar smell. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 265.12g/mol
-Melting point: 51-53 ℃
-Boiling point: no official data
-Solubility: Can be dissolved in organic solvents, such as ethanol, dimethylformamide, etc.
-Properties: It is a bromoalkanone compound with low toxicity and medium volatility.
Use:
-Pharmaceutical field: 2-bromo-1-(4-methoxyphenyl)propan-1-one has certain application value in the field of medicine. It can be used to synthesize biologically active compounds or participate in the drug synthesis process as an intermediate.
-Research field: In chemical research, it can be used as a starting material for synthetic materials or organic synthesis, including the synthesis of natural products.
Method:
2-bromo-1-(4-methoxyphenyl)propan-1-one can be synthesized by the following steps:
1.4-methoxyphenyl ethanol is reacted with bromoacetic acid to obtain 2-bromo -1-(4-methoxyphenyl) acetic acid.
2. The 2-bromo-1-(4-methoxyphenyl) acetic acid is reacted with acetic acid and anhydride or acid chlorination under base catalysis to give the final product 2-bromo-1-(4-methoxyphenyl)propan-1-one.
Safety Information:
- 2-bromo-1-(4-methoxyphenyl)propan-1-one requires attention to safety measures during operation, such as wearing appropriate protective gloves and glasses to ensure well-ventilated laboratory conditions.
-This compound should be kept away from ignition sources and avoid inhalation or contact with skin.
-During storage and use, please comply with all relevant laws and regulations, and follow the instructions provided by the safety data sheet.
Last Update:2024-04-09 19:05:47