2-Bromo-1-fluoro-3-nitrobenzene
2-Bromo-3-fluoronitrobenzene
CAS: 59255-94-6
Molecular Formula: C6H3BrFNO2
2-Bromo-1-fluoro-3-nitrobenzene - Names and Identifiers
| Name | 2-Bromo-3-fluoronitrobenzene |
| Synonyms | 2-broMo-3-fluorobroMobezene 2-Bromo-3-fluoronitrobenzene 2-BROMO-3-FLUORONITROBENZENE 2-Bromo-1-fluoro-3-nitrobenzene Benzene, 2-bromo-1-fluoro-3-nitro- |
| CAS | 59255-94-6 |
| EINECS | 1533716-785-6 |
| InChI | InChI=1/C6H3BrFNO2/c7-6-4(8)2-1-3-5(6)9(10)11/h1-3H |
2-Bromo-1-fluoro-3-nitrobenzene - Physico-chemical Properties
| Molecular Formula | C6H3BrFNO2 |
| Molar Mass | 220 |
| Density | 1.808±0.06 g/cm3(Predicted) |
| Melting Point | 42.0-44.0 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
| Boling Point | 222.3±20.0 °C(Predicted) |
| Flash Point | 88.3°C |
| Vapor Presure | 0.152mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.579 |
2-Bromo-1-fluoro-3-nitrobenzene - Risk and Safety
| Hazard Symbols | T - Toxic |
| Hazard Class | IRRITANT |
2-Bromo-1-fluoro-3-nitrobenzene - Introduction
2-Bromo-3-fluorontrobenzene is an organic compound with the chemical formula C6H3BrFNO2. The following is a description of the nature, use, preparation and safety information of 2-Bromo-3-fluoronirobenzene:
Nature:
-Appearance: colorless crystal or light yellow solid.
-Melting point: 55-58°C.
-Boiling point: 225-226°C.
-Density: 1.69g/cm³.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and dichloromethane.
Use:
-2-Bromo-3-fluorontrobenzene can be used as an organic synthesis intermediate. It can be used to synthesize drugs, dyes, pesticides and other organic compounds.
-It is also used to prepare other 2-bromo and 3-fluoro substituted nitrobenzene derivatives.
Preparation Method:
- 2-Bromo-3-fluoronitrobenzene can be prepared by nitrating 2-bromo-3-fluorobenzene. First, 2-bromo-3-fluorobenzene is reacted with nitric acid, and the electrophilic substitution reaction is carried out in the presence of nitric acid to give 2-Bromo-3-fluoronitrobenzene.
Safety Information:
-2-Bromo-3-fluoronirobenzene is an organic compound with certain toxicity. It can be harmful to the environment and should be handled and disposed of properly.
-Appropriate protective measures should be taken during the use, storage and handling of 2-Bromo-3-fluoronirobenzene, including the wearing of suitable personal protective equipment such as gloves, protective glasses and protective clothing.
-Avoid inhalation, ingestion and skin contact. Avoid dust, fumes or splashes of solution during operation.
-If contact or accidental inhalation occurs, immediately wash or take appropriate first aid measures, and seek medical help.
Nature:
-Appearance: colorless crystal or light yellow solid.
-Melting point: 55-58°C.
-Boiling point: 225-226°C.
-Density: 1.69g/cm³.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and dichloromethane.
Use:
-2-Bromo-3-fluorontrobenzene can be used as an organic synthesis intermediate. It can be used to synthesize drugs, dyes, pesticides and other organic compounds.
-It is also used to prepare other 2-bromo and 3-fluoro substituted nitrobenzene derivatives.
Preparation Method:
- 2-Bromo-3-fluoronitrobenzene can be prepared by nitrating 2-bromo-3-fluorobenzene. First, 2-bromo-3-fluorobenzene is reacted with nitric acid, and the electrophilic substitution reaction is carried out in the presence of nitric acid to give 2-Bromo-3-fluoronitrobenzene.
Safety Information:
-2-Bromo-3-fluoronirobenzene is an organic compound with certain toxicity. It can be harmful to the environment and should be handled and disposed of properly.
-Appropriate protective measures should be taken during the use, storage and handling of 2-Bromo-3-fluoronirobenzene, including the wearing of suitable personal protective equipment such as gloves, protective glasses and protective clothing.
-Avoid inhalation, ingestion and skin contact. Avoid dust, fumes or splashes of solution during operation.
-If contact or accidental inhalation occurs, immediately wash or take appropriate first aid measures, and seek medical help.
Last Update：2024-04-09 21:01:54
