2-Bromo-1-methoxy-4-(trifluoromethyl)benzene
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene
CAS: 402-10-8
Molecular Formula: C8H6BrF3O
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene - Names and Identifiers
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene - Physico-chemical Properties
| Molecular Formula | C8H6BrF3O |
| Molar Mass | 255.03 |
| Density | 1.6344 g/cm3 |
| Boling Point | 90-92 °C(Press: 10 Torr) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| Refractive Index | 1.4960 |
| MDL | MFCD03789249 |
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene - Introduction
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is an organic compound with the chemical formula C8H6BrF3O.
Nature:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is a colorless to pale yellow liquid. It has a strong gas, volatile, soluble in organic solvents such as alcohols and ketones. It is unstable to air and moisture and is difficult to preserve in its pure form.
Use:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is a common intermediate in organic synthesis, widely used in the preparation of pharmaceuticals, pesticides, dyes and chemical reagents. It can also be used in organic synthesis reactions, such as the oxidative coupling of alkyl halides.
Preparation Method:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is generally prepared by reacting trifluoromethylmagnesium chloride and bromomethyl ether in toluene. The reaction needs to be carried out under an inert atmosphere, and the reaction is controlled at a low temperature to avoid the occurrence of side reactions. The preparation process requires close attention to safe operation.
Safety Information:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is an organic compound, and its toxicity and irritation should be paid attention. Appropriate protective equipment such as gloves and goggles should be worn during handling and use to ensure good ventilation. Avoid contact with skin and inhalation of gas. If contact occurs, rinse immediately with plenty of water and seek medical help.
Nature:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is a colorless to pale yellow liquid. It has a strong gas, volatile, soluble in organic solvents such as alcohols and ketones. It is unstable to air and moisture and is difficult to preserve in its pure form.
Use:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is a common intermediate in organic synthesis, widely used in the preparation of pharmaceuticals, pesticides, dyes and chemical reagents. It can also be used in organic synthesis reactions, such as the oxidative coupling of alkyl halides.
Preparation Method:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is generally prepared by reacting trifluoromethylmagnesium chloride and bromomethyl ether in toluene. The reaction needs to be carried out under an inert atmosphere, and the reaction is controlled at a low temperature to avoid the occurrence of side reactions. The preparation process requires close attention to safe operation.
Safety Information:
2-Bromo-1-methoxy-4-(trifluoromethyl)benzene is an organic compound, and its toxicity and irritation should be paid attention. Appropriate protective equipment such as gloves and goggles should be worn during handling and use to ensure good ventilation. Avoid contact with skin and inhalation of gas. If contact occurs, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:18:08
