2-Bromo-3-chloropyridine
2-Bromo-3-chloropyridine
CAS: 96424-68-9
Molecular Formula: C5H3BrClN
2-Bromo-3-chloropyridine - Names and Identifiers
| Name | 2-Bromo-3-chloropyridine |
| Synonyms | 3-chloro-2-bromopyridine 2-BROMO-3-CHLOROPYRIDINE 2-Bromo-3-chloropyridine 2-bromo-3-pyridyl chloride Pyridine, 2-bromo-3-chloro- |
| CAS | 96424-68-9 |
| EINECS | 678-771-3 |
| InChI | InChI=1/C5H3BrClN/c6-5-4(7)2-1-3-8-5/h1-3H |
2-Bromo-3-chloropyridine - Physico-chemical Properties
| Molecular Formula | C5H3BrClN |
| Molar Mass | 192.44 |
| Density | 1.736±0.06 g/cm3(Predicted) |
| Melting Point | 58-63 °C |
| Boling Point | 223.9±20.0 °C(Predicted) |
| Flash Point | 89.2°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.14mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| BRN | 1561638 |
| pKa | -1.49±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.581 |
| MDL | MFCD04039344 |
2-Bromo-3-chloropyridine - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
| Packing Group | I |
2-Bromo-3-chloropyridine - Introduction
2-Bromo-3-chloroopyridine is an organic compound with the chemical formula C5H3BrClN. It is a solid and colorless crystalline substance.
Here are some of the properties of 2-Bromo-3-chlorostyridine:
-Melting Point: 76-78°C
-Boiling Point: 234-236°C
-Density: approx. 1.8g/cm³
-Solubility: It is soluble in organic solvents (such as ethanol, acetone and dimethylformamide) and insoluble in water.
2-Bromo-3-chloropyridine has a wide range of applications in organic synthesis:
-It can be used as an intermediate in organic synthesis and used to synthesize other compounds.
-Because it has chlorine and bromine functional groups, it can be used to construct specific bonds in molecular structures.
-It can also be used as a prodrug for biologically active molecules.
The process for preparing 2-Bromo-3-chloropyridine generally involves the reaction of 3-chloropyridine and bromoethane. The steps and conditions of the specific preparation method can be adjusted according to the desired yield and purity.
Regarding safety information, 2-bromo-3-chloropyridine is a chemical that may be harmful to humans and the environment. Appropriate safety precautions shall be taken during use and handling:
-Wear personal protective equipment such as safety glasses, gloves and protective clothing during operation.
-Avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water.
-Use in a well-ventilated place to avoid inhaling aerosols or dust.
-Waste should be disposed of in accordance with local regulations.
Here are some of the properties of 2-Bromo-3-chlorostyridine:
-Melting Point: 76-78°C
-Boiling Point: 234-236°C
-Density: approx. 1.8g/cm³
-Solubility: It is soluble in organic solvents (such as ethanol, acetone and dimethylformamide) and insoluble in water.
2-Bromo-3-chloropyridine has a wide range of applications in organic synthesis:
-It can be used as an intermediate in organic synthesis and used to synthesize other compounds.
-Because it has chlorine and bromine functional groups, it can be used to construct specific bonds in molecular structures.
-It can also be used as a prodrug for biologically active molecules.
The process for preparing 2-Bromo-3-chloropyridine generally involves the reaction of 3-chloropyridine and bromoethane. The steps and conditions of the specific preparation method can be adjusted according to the desired yield and purity.
Regarding safety information, 2-bromo-3-chloropyridine is a chemical that may be harmful to humans and the environment. Appropriate safety precautions shall be taken during use and handling:
-Wear personal protective equipment such as safety glasses, gloves and protective clothing during operation.
-Avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water.
-Use in a well-ventilated place to avoid inhaling aerosols or dust.
-Waste should be disposed of in accordance with local regulations.
Last Update：2024-04-09 21:04:16
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