2-Bromo-3-fluoropyridine
2-Bromo-3-fluoropyridine
CAS: 40273-45-8
Molecular Formula: C5H3BrFN
2-Bromo-3-fluoropyridine - Names and Identifiers
2-Bromo-3-fluoropyridine - Physico-chemical Properties
| Molecular Formula | C5H3BrFN |
| Molar Mass | 175.99 |
| Density | 1.74 |
| Boling Point | 62°C |
| Appearance | clear liquid |
| Color | Colorless to Light yellow to Light orange |
| pKa | -1.63±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.5450 |
2-Bromo-3-fluoropyridine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| UN IDs | 1993 |
| HS Code | 29333990 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
2-Bromo-3-fluoropyridine - Introduction
2-Bromo-3-fluoropyridine is an organic compound with the chemical formula C5H3BrFN. The following is a description of its nature, use, formulation and safety information:
Nature:
2-Bromo-3-fluoropyridine is a colorless liquid with a high density and a high boiling point. It has an aromatic odor similar to pyridine.
Use:
2-Bromo-3-fluoropyridine is widely used in chemical reactions in organic synthesis. It is often used as an intermediate in the manufacture of pesticides, pharmaceuticals and other organic compounds.
Preparation Method:
The preparation of 2-Bromo-3-fluoropyridine can be achieved by the fluorination and bromination of pyridine. First, pyridine is reacted with hydrogen fluoride to obtain 2-fluoropyridine. Then, 2-fluoropyridine is reacted with bromine to give the target product 2-Bromo-3-fluoropyridine.
Safety Information:
When using and storing 2-Bromo-3-fluoropyridine, you need to pay attention to the following safety matters:
1. This compound is irritating and can cause discomfort to the eyes, skin and respiratory tract. Avoid direct contact when using.
2. Need to operate in a well-ventilated place to avoid inhaling its vapor.
3. During operation or storage, care should be taken to avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
4. Wear appropriate protective equipment such as chemical protective gloves and goggles when handling the compound.
5. During storage, it should be stored in a sealed container, away from fire sources and combustibles.
Please note that when handling and using any chemicals, you should follow the correct laboratory safety procedures and assess the risks according to the specific situation.
Nature:
2-Bromo-3-fluoropyridine is a colorless liquid with a high density and a high boiling point. It has an aromatic odor similar to pyridine.
Use:
2-Bromo-3-fluoropyridine is widely used in chemical reactions in organic synthesis. It is often used as an intermediate in the manufacture of pesticides, pharmaceuticals and other organic compounds.
Preparation Method:
The preparation of 2-Bromo-3-fluoropyridine can be achieved by the fluorination and bromination of pyridine. First, pyridine is reacted with hydrogen fluoride to obtain 2-fluoropyridine. Then, 2-fluoropyridine is reacted with bromine to give the target product 2-Bromo-3-fluoropyridine.
Safety Information:
When using and storing 2-Bromo-3-fluoropyridine, you need to pay attention to the following safety matters:
1. This compound is irritating and can cause discomfort to the eyes, skin and respiratory tract. Avoid direct contact when using.
2. Need to operate in a well-ventilated place to avoid inhaling its vapor.
3. During operation or storage, care should be taken to avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
4. Wear appropriate protective equipment such as chemical protective gloves and goggles when handling the compound.
5. During storage, it should be stored in a sealed container, away from fire sources and combustibles.
Please note that when handling and using any chemicals, you should follow the correct laboratory safety procedures and assess the risks according to the specific situation.
Last Update：2024-04-09 21:01:54
