2-Bromo-4-(trifluoromethyl)phenylacetonitrile
2-Bromo-4-(trifluoromethyl)phenylacetonitrile
CAS: 474024-36-7
Molecular Formula: C9H5BrF3N
2-Bromo-4-(trifluoromethyl)phenylacetonitrile - Names and Identifiers
| Name | 2-Bromo-4-(trifluoromethyl)phenylacetonitrile |
| Synonyms | 2-BROMO-4-(TRIFLUOROMETHYL)PHENYLACETONITRILE 2-Bromo-4-(trifluoromethyl)phenylacetonitrile [2-Bromo-4-(trifluoromethyl)phenyl]acetonitrile Benzeneacetonitrile, 2-broMo-4-(trifluoroMethyl)- benzeneacetonitrile, 2-bromo-4-(trifluoromethyl)- 2-(2-bromo-4-(trifluoromethyl)phenyl)acetonitrile |
| CAS | 474024-36-7 |
| InChI | InChI=1/C9H5BrF3N/c10-8-5-7(9(11,12)13)2-1-6(8)3-4-14/h1-2,5H,3H2 |
2-Bromo-4-(trifluoromethyl)phenylacetonitrile - Physico-chemical Properties
| Molecular Formula | C9H5BrF3N |
| Molar Mass | 264.04 |
| Density | 1.626g/mLat 25°C(lit.) |
| Boling Point | 265-266°C(lit.) |
| Flash Point | ≤230°F |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.00767mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.5020(lit.) |
2-Bromo-4-(trifluoromethyl)phenylacetonitrile - Risk and Safety
| WGK Germany | 3 |
| Hazard Note | Toxic |
2-Bromo-4-(trifluoromethyl)phenylacetonitrile - Introduction
2-Bromo-4-(trifluoromethyl)phenylacetonitrile is an organic compound with the chemical formula C9H5BrF3N.
Nature:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile is a colorless to slightly yellow liquid. It has one bromine atom and three fluorine atoms attached to the carbon atoms of the benzene ring. It is an organic halide and nitrile compound.
Use:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile are useful as intermediates in organic synthesis. It is widely used in medicine, pesticide and other organic synthesis fields. It can be used to synthesize fluorine-containing organic compounds, and can also be used as a starting material for the synthesis of aromatic compounds.
Preparation Method:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile can be synthesized by reacting sodium cyanide on 2-bromo-4-trifluoromethylbenzene. First, sodium cyanide and trifluoromethylacetophenone are reacted in a solvent such as acetonitrile to produce 2-bromo-4-trifluoromethylacetophenone. The 2-Bromo-4-(trifluoromethyl)phenylacetonitrile is then obtained by dehydrogenation and nitrification.
Safety Information:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile should be treated in accordance with the routine operation of organic compounds to avoid contact with skin and eyes. Necessary protective measures, such as wearing protective gloves, goggles and protective clothing, are required during use or operation. Good ventilation should be maintained during use. If ingested or inhaled by mistake, please seek medical attention in time.
Nature:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile is a colorless to slightly yellow liquid. It has one bromine atom and three fluorine atoms attached to the carbon atoms of the benzene ring. It is an organic halide and nitrile compound.
Use:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile are useful as intermediates in organic synthesis. It is widely used in medicine, pesticide and other organic synthesis fields. It can be used to synthesize fluorine-containing organic compounds, and can also be used as a starting material for the synthesis of aromatic compounds.
Preparation Method:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile can be synthesized by reacting sodium cyanide on 2-bromo-4-trifluoromethylbenzene. First, sodium cyanide and trifluoromethylacetophenone are reacted in a solvent such as acetonitrile to produce 2-bromo-4-trifluoromethylacetophenone. The 2-Bromo-4-(trifluoromethyl)phenylacetonitrile is then obtained by dehydrogenation and nitrification.
Safety Information:
2-Bromo-4-(trifluoromethyl)phenylacetonitrile should be treated in accordance with the routine operation of organic compounds to avoid contact with skin and eyes. Necessary protective measures, such as wearing protective gloves, goggles and protective clothing, are required during use or operation. Good ventilation should be maintained during use. If ingested or inhaled by mistake, please seek medical attention in time.
Last Update：2024-04-09 21:01:54
