2-Bromo-4-fluoropyridine
2-Bromo-4-fluoropyridine
CAS: 357927-50-5
Molecular Formula: C5H3BrFN
2-Bromo-4-fluoropyridine - Names and Identifiers
| Name | 2-Bromo-4-fluoropyridine |
| Synonyms | 2-Brom-4-fluorpyridin 2-Bromo-4-fluoropyridine Pyridine, 2-bromo-4-fluoro- |
| CAS | 357927-50-5 |
| InChI | InChI=1/C5H3BrFN/c6-5-3-4(7)1-2-8-5/h1-3H |
| InChIKey | AIEATTRZKVGMBO-UHFFFAOYSA-N |
2-Bromo-4-fluoropyridine - Physico-chemical Properties
| Molecular Formula | C5H3BrFN |
| Molar Mass | 175.99 |
| Density | 1.699 g/mL at 25 °C |
| Boling Point | 188.8±20.0 °C(Predicted) |
| Flash Point | 76°(169°F) |
| Vapor Presure | 0.813mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless to Light yellow |
| pKa | -0.33±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.5370 |
| MDL | MFCD09260909 |
2-Bromo-4-fluoropyridine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 1 |
| HS Code | 29333990 |
2-Bromo-4-fluoropyridine - Introduction
2-Bromo-4-fluoropyridine is an organic compound whose chemical formula is C5H3BrFN. It has the following properties:
Physical Properties:
Appearance: colorless liquid
Density: 1.76g/cm³
Boiling point: 162-164°C
Melting point:-1°C
Chemical Properties:
2-Bromo-4-fluoropyridine is an organic halide, which often exhibits alkaline characteristics in chemical reactions.
Use:
2-Bromo-4-fluoropyridine is an important organic synthesis intermediate, widely used in the preparation of various organic compounds, including pharmaceuticals, pesticides and dyes. It has important application value in the field of medicinal chemistry and agricultural science.
Preparation Method:
The preparation method of 2-Bromo-4-fluoropyridine is relatively simple. A common method is to react 4-fluoropyridine and copper bromide (CuBr) in the presence of ethylene oxide (ethylene oxide) to generate the target product.
Safety Information:
The safety and toxicity data of 2-Bromo-4-fluoropyridine are rarely reported, so protective measures should be paid attention to when using it. It may cause irritation to the skin, eyes and mucous membranes, so wear appropriate protective gloves, glasses and a mask during operation. At the same time, ensure that the operation is carried out in a well-ventilated place and avoid exposure to fire and high temperature. In the event of an accident, flush with water immediately and seek timely medical help. When handling and storing, please refer to the relevant safety procedures and operate in accordance with local regulations.
Physical Properties:
Appearance: colorless liquid
Density: 1.76g/cm³
Boiling point: 162-164°C
Melting point:-1°C
Chemical Properties:
2-Bromo-4-fluoropyridine is an organic halide, which often exhibits alkaline characteristics in chemical reactions.
Use:
2-Bromo-4-fluoropyridine is an important organic synthesis intermediate, widely used in the preparation of various organic compounds, including pharmaceuticals, pesticides and dyes. It has important application value in the field of medicinal chemistry and agricultural science.
Preparation Method:
The preparation method of 2-Bromo-4-fluoropyridine is relatively simple. A common method is to react 4-fluoropyridine and copper bromide (CuBr) in the presence of ethylene oxide (ethylene oxide) to generate the target product.
Safety Information:
The safety and toxicity data of 2-Bromo-4-fluoropyridine are rarely reported, so protective measures should be paid attention to when using it. It may cause irritation to the skin, eyes and mucous membranes, so wear appropriate protective gloves, glasses and a mask during operation. At the same time, ensure that the operation is carried out in a well-ventilated place and avoid exposure to fire and high temperature. In the event of an accident, flush with water immediately and seek timely medical help. When handling and storing, please refer to the relevant safety procedures and operate in accordance with local regulations.
Last Update：2024-04-09 21:11:58
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View History
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