2-Bromo-4-methylpyrimidine - Names and Identifiers
2-Bromo-4-methylpyrimidine - Physico-chemical Properties
Molecular Formula | C5H5BrN2
|
Molar Mass | 173.01 |
Density | 1.596±0.06 g/cm3(Predicted) |
Melting Point | 45-50℃ |
Boling Point | 265.0±33.0 °C(Predicted) |
Flash Point | 114.044°C |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.015mmHg at 25°C |
Appearance | White to light yellow to brown powder or crystal |
pKa | -1.06±0.20(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.558 |
MDL | MFCD04037883 |
2-Bromo-4-methylpyrimidine - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
|
WGK Germany | 3 |
HS Code | 29335990 |
Hazard Class | IRRITANT |
2-Bromo-4-methylpyrimidine - Introduction
2-Bromo-4-methylpyrimidine is an organic compound with the chemical formula C6H6BrN2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-bromo-4-methylpyrimidine is white crystal or crystalline powder.
-Solubility: It is soluble in water, alcohols and some organic solvents.
Use:
2-Bromo-4-methylpyrimidine has a wide range of applications in the chemical field, such:
-As an intermediate of pyrimidine catalysts, it plays an important role in organic synthesis reactions.
-Used as a raw material for drugs, such as in the synthesis of certain anti-cancer drugs.
Preparation Method:
The preparation method of 2-bromo-4-methylpyrimidine can be carried out by the following steps:
-First, 2-methyl pyrimidine is reacted with bromine to generate 2-bromo-4-methylpyrimidine.
-The reaction is usually carried out in a suitable solvent (such as ethanol), enough bromine is added, and the yield and purity are controlled by controlling the reaction conditions (such as temperature and reaction time).
Safety Information:
-2-Bromo-4-methylpyrimidine is irritating to the skin and eyes.
-During operation, avoid direct contact with skin and eyes, and take appropriate protective measures, such as wearing goggles and gloves.
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-Storage should be sealed and kept away from fire and oxidizing agents.
Last Update:2024-04-09 21:01:54