2-Bromo-4-nitro-6-(trifluoromethyl)aniline
2-Bromo-4-nitro-6-(trifluoromethyl)aniline
CAS: 400-66-8
Molecular Formula: C7H4BrF3N2O2
2-Bromo-4-nitro-6-(trifluoromethyl)aniline - Names and Identifiers
2-Bromo-4-nitro-6-(trifluoromethyl)aniline - Physico-chemical Properties
| Molecular Formula | C7H4BrF3N2O2 |
| Molar Mass | 285.02 |
| Density | 1.859±0.06 g/cm3(Predicted) |
| Melting Point | 140-142 °C |
| Boling Point | 306.8±37.0 °C(Predicted) |
| pKa | -4.03±0.46(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD14560537 |
2-Bromo-4-nitro-6-(trifluoromethyl)aniline - Risk and Safety
| Hazard Class | IRRITANT |
2-Bromo-4-nitro-6-(trifluoromethyl)aniline - Introduction
2-Bromo-4-nitro-6-(trifluoromethyl)aniline is an organic compound with the chemical formula C6H3BrF3N2O2. It is a yellow crystalline solid and is soluble in some organic solvents such as ethanol and chloride at room temperature.
One of its main uses is as an intermediate in organic synthesis, especially in pharmaceutical synthesis. It can be used to synthesize some organic dyes, pharmaceuticals and pesticides. In addition, it can also be used as a nitro reagent and a photosensitizer.
Preparation of 2-Bromo-4-nitro-6-(trifluoromethyl)aniline can be obtained by trifluoromethylation of 2-bromo-4-nitro-6-methylaniline. In this reaction, trifluoromethanesulfonic acid or trifluoromethylsulfonyl fluoride can be used as the trifluoromethylating agent.
Regarding safety information, 2-Bromo-4-nitro-6-(trifluoromethyl)aniline should be careful to protect the skin and eyes during use and storage, and avoid contact and inhalation of the compound. The operation needs to be carried out in a well-ventilated environment, and necessary personal protective measures should be taken, such as wearing gloves and face masks. In addition, proper laboratory safety practices should be followed for handling and disposal.
One of its main uses is as an intermediate in organic synthesis, especially in pharmaceutical synthesis. It can be used to synthesize some organic dyes, pharmaceuticals and pesticides. In addition, it can also be used as a nitro reagent and a photosensitizer.
Preparation of 2-Bromo-4-nitro-6-(trifluoromethyl)aniline can be obtained by trifluoromethylation of 2-bromo-4-nitro-6-methylaniline. In this reaction, trifluoromethanesulfonic acid or trifluoromethylsulfonyl fluoride can be used as the trifluoromethylating agent.
Regarding safety information, 2-Bromo-4-nitro-6-(trifluoromethyl)aniline should be careful to protect the skin and eyes during use and storage, and avoid contact and inhalation of the compound. The operation needs to be carried out in a well-ventilated environment, and necessary personal protective measures should be taken, such as wearing gloves and face masks. In addition, proper laboratory safety practices should be followed for handling and disposal.
Last Update：2024-04-09 20:52:54
