2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
2-Bromo-5-pyridylboronic acid pinacol ester
CAS: 214360-62-0
Molecular Formula: C11H15BBrNO2
2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Names and Identifiers
2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Physico-chemical Properties
| Molecular Formula | C11H15BBrNO2 |
| Molar Mass | 283.96 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Boling Point | 345.1±27.0 °C(Predicted) |
| Flash Point | 162.5°C |
| Vapor Presure | 0.000126mmHg at 25°C |
| pKa | 0.78±0.12(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.527 |
| MDL | MFCD03412794 |
2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Class | IRRITANT |
2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Introduction
2-Bromo-5-pyridylboronic acid pinacol ester(2-Bromo-5-pyridylboronic acid pinacol ester) is an organic compound with the following properties:
1. Appearance: White crystalline solid.
2. Molecular formula: C12H16BBrNO2.
3. Molecular weight: 284.07g/mol.
4. Melting Point: about 80-82 degrees Celsius.
The main use of this compound is as an important reagent in organic synthesis. It can be used in the synthesis of various organic compounds containing 2-bromo-5-pyridyl. For example, it can be used as a substrate to react with other compounds in a cross-coupling reaction to generate new compounds. In addition, it can also be used in the synthesis of important intermediates in organic synthesis.
The method of preparing 2-Bromo-5-pyridylboronic acid pinacol ester is generally carried out by the following steps:
1. Reacting 2-bromo -5-bromopyridine with pinacol ester to generate 2-bromo -5-pinacol ester;
2. 2-bromo-5-pinacol ester reacts with boric acid to generate 2-bromo-5-pyridyylboronic acid pinacol ester.
When using 2-Bromo-5-pyridylboronic acid pinacol ester, you need to pay attention to the following safety information:
1. This compound has a certain degree of irritation, contact with the eyes, skin and respiratory tract should be avoided.
2. Wear appropriate protective equipment during operation, such as safety glasses, protective gloves and protective clothing.
3. It should be operated in a well-ventilated laboratory environment and avoid inhaling volatile gases.
4. In the storage and disposal process to comply with the relevant safety procedures and regulations.
It is best to operate and process under the guidance of a laboratory or professional.
1. Appearance: White crystalline solid.
2. Molecular formula: C12H16BBrNO2.
3. Molecular weight: 284.07g/mol.
4. Melting Point: about 80-82 degrees Celsius.
The main use of this compound is as an important reagent in organic synthesis. It can be used in the synthesis of various organic compounds containing 2-bromo-5-pyridyl. For example, it can be used as a substrate to react with other compounds in a cross-coupling reaction to generate new compounds. In addition, it can also be used in the synthesis of important intermediates in organic synthesis.
The method of preparing 2-Bromo-5-pyridylboronic acid pinacol ester is generally carried out by the following steps:
1. Reacting 2-bromo -5-bromopyridine with pinacol ester to generate 2-bromo -5-pinacol ester;
2. 2-bromo-5-pinacol ester reacts with boric acid to generate 2-bromo-5-pyridyylboronic acid pinacol ester.
When using 2-Bromo-5-pyridylboronic acid pinacol ester, you need to pay attention to the following safety information:
1. This compound has a certain degree of irritation, contact with the eyes, skin and respiratory tract should be avoided.
2. Wear appropriate protective equipment during operation, such as safety glasses, protective gloves and protective clothing.
3. It should be operated in a well-ventilated laboratory environment and avoid inhaling volatile gases.
4. In the storage and disposal process to comply with the relevant safety procedures and regulations.
It is best to operate and process under the guidance of a laboratory or professional.
Last Update：2024-04-10 22:29:15
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Product Name: 2-Bromopyridine-5-boronic acid pinacol ester Visit Supplier Webpage Request for quotation
CAS: 214360-62-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 214360-62-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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