2-Bromo-5-(trifluoromethyl)benzaldehyde

2-Bromo-5-(trifluoromethyl)benzaldehyde - Names and Identifiers

Name	2-Bromo-5-(trifluoromethyl)benzaldehyde
Synonyms	trans-4,4'-Difluorochalcone 4-Bromo-3-formylbenzotrifluoride 2-Bromo-5-Trifluoromethylbenzaldehyde 2-Bromo-5-(trifluoromethyl)benzaldehyde Benzaldehyde, 2-bromo-5-(trifluoromethyl)- (2E)-1,3-Bis(4-fluorophenyl)-2-propen-1-one (2E)-1,3-bis(4-fluorophenyl)prop-2-en-1-one 2-propen-1-one, 1,3-bis(4-fluorophenyl)-, (2E)- 4-Bromo-3-formylbenzotrifluoride, 6-Bromo-alpha,alpha,alpha-trifluoro-m-tolualdehyde
CAS	875664-28-1 102684-91-3
InChI	InChI=1/C8H4BrF3O/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-4H

2-Bromo-5-(trifluoromethyl)benzaldehyde - Physico-chemical Properties

Molecular Formula	C8H4BrF3O
Molar Mass	253.02
Density	1.677±0.06 g/cm3(Predicted)
Boling Point	239.1±35.0 °C(Predicted)
Flash Point	98.4°C
Vapor Presure	0.0408mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive
Refractive Index	1.511

2-Bromo-5-(trifluoromethyl)benzaldehyde - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

2-Bromo-5-(trifluoromethyl)benzaldehyde - Introduction

2-Bromo-5-(trifluoromethyl)benzaldehyde is an organic compound whose chemical structural formula is Br-C6H3(CF3)CHO. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to yellow crystal or solid
-Solubility: Soluble in most organic solvents, such as ether, alcohol and dimethyl ketone
-Melting point: about 58-60 ℃
-Boiling point: about 150-152 ℃
-Molecular weight: about 261.03g/mol

Use:
2-Bromo-5-(trifluoromethyl)benzaldehyde has certain application value in organic synthesis and is commonly used in the following aspects:
-Used as raw materials and intermediates in organic synthesis
-Can be used to prepare other organic compounds, such as drugs, pesticides and dyes
-In the field of materials science, it can be used to prepare polymers containing specific functional groups

Preparation Method:
The preparation method of 2-Bromo-5-(trifluoromethyl)benzaldehyde can be achieved by the following steps:
1. Add p-dibromobenzene (2-bromo-phenyl), trifluoroformic acid (trifluoroacetic acid) and ferric chloride (ferric chloride) to the mixed solvent.
2. Stir the reaction mixture under appropriate temperature conditions to cause the corresponding reaction.
3. The product was filtered, crystallized and isolated.
4. Through appropriate purification steps, pure 2-Bromo-5-(trifluoromethyl)benzaldehyde is obtained.

Safety Information:
2-Bromo-5-(trifluoromethyl)benzaldehyde need to pay attention to the following safety matters during use:
-If inhaled, immediately stay away from the site and breathe in fresh air.
-Avoid contact with skin and eyes and avoid swallowing.
-In the event of exposure to the compound, rinse the affected area immediately with plenty of water.
-If taken by mistake, seek medical advice immediately and bring the compound's packaging or label.

Last Update：2024-04-09 19:05:52