2-Bromo-5-chloronicotinonitrile
2-Bromo-5-chloronicotinonitrile
CAS: 1256823-81-0
Molecular Formula: C6H2BrClN2
2-Bromo-5-chloronicotinonitrile - Names and Identifiers
| Name | 2-Bromo-5-chloronicotinonitrile |
| Synonyms | 2-Bromo-5-chloronicotinonitrile 2-BroMo-5-chloronicotinonitrile 2-bromo-5-chloro-3-cyanopyridine 2-Bromo-5-chloropyridine-3-carbonitrile 3-Pyridinecarbonitrile, 2-bromo-5-chloro- |
| CAS | 1256823-81-0 |
| InChI | InChI=1S/C6H2BrClN2/c7-6-4(2-9)1-5(8)3-10-6/h1,3H |
2-Bromo-5-chloronicotinonitrile - Physico-chemical Properties
| Molecular Formula | C6H2BrClN2 |
| Molar Mass | 217.45 |
| Density | 1.85 |
| Boling Point | 285℃ |
| Flash Point | 126℃ |
| pKa | -4.94±0.20(Predicted) |
2-Bromo-5-chloronicotinonitrile - Introduction
2-Bromo-5-chloro-3-cyanopyridine is an organic compound with the chemical formula C7H3BrClN. It is a solid substance with a white to light yellow color.
This compound has some important properties and uses. First of all, it is an important organic synthesis intermediate, which can be used to synthesize various functionalized pyridine compounds.
Secondly, 2-bromo-5-chloro-3-cyanopyridine has strong antibacterial and fungicidal activities, so it can be used as an insecticide or fungicide in agriculture. It is also used as one of the raw materials for dye synthesis.
There are various methods for preparing 2-bromo-5-chloro-3-cyanopyridine, and the common method has two-step reaction. First, 2-cyanopyridine is obtained by reacting hydrogen cyanide with pyridine. 2-Cyanopyridine is then reacted with hydrobromic acid and ferric chloride to give 2-bromo-5-chloro-3-cyanopyridine.
When using and storing this compound, you need to pay attention to its safety information. 2-bromo -5-chloro -3-cyanopyridine belongs to organic halogen compound, which is irritating and toxic. In the operation, should wear appropriate protective measures, such as wear gloves, goggles, etc. In addition, it should be kept away from open flames and heat sources, and stored in a cool and dry place, away from acids, alkalis and other substances that should not be mixed. If contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
This compound has some important properties and uses. First of all, it is an important organic synthesis intermediate, which can be used to synthesize various functionalized pyridine compounds.
Secondly, 2-bromo-5-chloro-3-cyanopyridine has strong antibacterial and fungicidal activities, so it can be used as an insecticide or fungicide in agriculture. It is also used as one of the raw materials for dye synthesis.
There are various methods for preparing 2-bromo-5-chloro-3-cyanopyridine, and the common method has two-step reaction. First, 2-cyanopyridine is obtained by reacting hydrogen cyanide with pyridine. 2-Cyanopyridine is then reacted with hydrobromic acid and ferric chloride to give 2-bromo-5-chloro-3-cyanopyridine.
When using and storing this compound, you need to pay attention to its safety information. 2-bromo -5-chloro -3-cyanopyridine belongs to organic halogen compound, which is irritating and toxic. In the operation, should wear appropriate protective measures, such as wear gloves, goggles, etc. In addition, it should be kept away from open flames and heat sources, and stored in a cool and dry place, away from acids, alkalis and other substances that should not be mixed. If contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
