2-Bromo-5-chloropyrimidine

2-Bromo-5-chloropyrimidine - Names and Identifiers

Name	Pyrimidine, 2-bromo-5-chloro-
Synonyms	2-Bromo-5-chloropyrimidine 5-Chloro-2-bromopyrimidine Pyrimidine, 2-bromo-5-chloro-
CAS	124405-67-0
InChI	InChI=1/C4H2BrClN2/c5-4-7-1-3(6)2-8-4/h1-2H

2-Bromo-5-chloropyrimidine - Physico-chemical Properties

Molecular Formula	C4H2BrClN2
Molar Mass	193.43
Density	1.859
Boling Point	291℃
Flash Point	130℃
Vapor Presure	0.003mmHg at 25°C
pKa	-2.97±0.22(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.588

2-Bromo-5-chloropyrimidine - Introduction

2-Bromo-5-chloropyrimidine is an organic compound with the chemical formula C5H3BrClN2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2-Bromo-5-chloropyrimidine is a colorless to slightly yellow crystal.
-Melting point: approximately 80-82°C.
-Solubility: In common organic solvents, such as alcohols and ethers, can be dissolved.
-Stability: relatively stable at room temperature.

Use:
-2-Bromo-5-chloropyrimidine is often used as a starting material and intermediate in organic synthesis. It can be used to prepare various organic compounds containing pyrimidine structure, such as pesticides, drugs, etc.

Preparation Method:
2-Bromo-5-chloropyrimidine can be prepared by the following two methods:
1. 2-bromo-5-chloropyrimidine is obtained by reacting 5-chloropyrimidine with bromine to replace chlorine atom with bromine atom.
2. 2-bromo-5-chloropyrimidine is obtained by reacting 2-bromopyrimidine with chlorine to replace bromine atom with chlorine atom.

Safety Information:
-2-Bromo-5-chloropyrimidine is an organic compound and should be kept away from heat sources, open flames and oxidants to avoid fire or explosion.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing during use or preparation.
-If you come into contact with this compound, rinse immediately with plenty of water and seek medical help.
-It should be stored in an airtight container, away from sunlight and moisture.

Please note that the specific use and safety of 2-bromo-5-chloropyrimidine will be affected by the required chemical reaction conditions and the use environment. Therefore, it is necessary to operate with caution and follow relevant safety procedures in practical applications.

Last Update：2024-04-09 15:17:51