2-Bromo-5-methoxyaniline
2-Bromo-5-methoxyaniline
CAS: 59557-92-5
Molecular Formula: C7H8BrNO
2-Bromo-5-methoxyaniline - Names and Identifiers
| Name | 2-Bromo-5-methoxyaniline |
| Synonyms | 2-BROMO-5-METHOXYANI 4-Bromo-3-amino anisole 2-BROMO-5-METHOXYANILINE 2-Bromo-5-methoxyaniline 2-bromo-5-methoxybenzenamine 2-BroMo-5-Methoxy-phenylaMine 2-Bromo-5-methoxy-phenylamine benzenamine, 2-bromo-5-methoxy- 2-Bromo-5-Methoxyaniline (In HCl salt form) 3-Amino-4-bromoanisole, 6-Bromo-m-anisidine |
| CAS | 59557-92-5 |
| EINECS | 611-853-9 |
| InChI | InChI=1/C7H8BrNO/c1-10-5-2-3-6(8)7(9)4-5/h2-4H,9H2,1H3 |
2-Bromo-5-methoxyaniline - Physico-chemical Properties
| Molecular Formula | C7H8BrNO |
| Molar Mass | 202.05 |
| Density | 1.531±0.06 g/cm3(Predicted) |
| Melting Point | 189-190°C |
| Boling Point | 280.1±20.0 °C(Predicted) |
| Flash Point | 123.173°C |
| Vapor Presure | 0.004mmHg at 25°C |
| Appearance | White powder |
| pKa | 2.11±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.596 |
2-Bromo-5-methoxyaniline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| HS Code | 29222990 |
2-Bromo-5-methoxyaniline - Introduction
2-Bromo-5-methoxyaniline is an organic compound with the chemical formula of C7H8BrNO and CAS number 58456-63-8. It is a colorless to pale yellow crystal. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: about 66-68 ℃
-Boiling point: about 250-300 ℃
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane, insoluble in water
Use:
- 2-Bromo-5-methoxyaniline can be used as catalysts and intermediates in organic synthesis reactions.
-It is also used to synthesize biologically active molecules in the pharmaceutical field.
Preparation Method:
The preparation method of 2-Bromo-5-methoxyaniline can be carried out by the following steps:
-First, dissolve p-methoxyaniline in an organic solvent.
-Then, add cuprous bromide (CuBr) and sodium bicarbonate anhydride (NaHCO3) to the solution.
-Under appropriate reaction conditions, react for several hours.
-After the reaction is completed, the product is purified by water washing and distillation.
Safety Information:
- 2-Bromo-5-methoxyaniline is an organic compound, and laboratory safety regulations should be followed during operation.
-It may cause irritation to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as gloves, safety glasses and masks during operation.
-During storage and handling, care should be taken to avoid contact with oxidants, strong acids or strong bases to avoid dangerous chemical reactions.
-When disposing of waste, follow local environmental regulations and choose the appropriate disposal method.
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: about 66-68 ℃
-Boiling point: about 250-300 ℃
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane, insoluble in water
Use:
- 2-Bromo-5-methoxyaniline can be used as catalysts and intermediates in organic synthesis reactions.
-It is also used to synthesize biologically active molecules in the pharmaceutical field.
Preparation Method:
The preparation method of 2-Bromo-5-methoxyaniline can be carried out by the following steps:
-First, dissolve p-methoxyaniline in an organic solvent.
-Then, add cuprous bromide (CuBr) and sodium bicarbonate anhydride (NaHCO3) to the solution.
-Under appropriate reaction conditions, react for several hours.
-After the reaction is completed, the product is purified by water washing and distillation.
Safety Information:
- 2-Bromo-5-methoxyaniline is an organic compound, and laboratory safety regulations should be followed during operation.
-It may cause irritation to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as gloves, safety glasses and masks during operation.
-During storage and handling, care should be taken to avoid contact with oxidants, strong acids or strong bases to avoid dangerous chemical reactions.
-When disposing of waste, follow local environmental regulations and choose the appropriate disposal method.
Last Update：2024-04-09 21:01:54
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CAS: 59557-92-5
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QQ: 3008007409
Wechat: 18301782025
CAS: 59557-92-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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