2-Bromo-5-trifluoromethoxypyridine
2-Bromo-5-trifluoromethoxypyridine
CAS: 888327-36-4
Molecular Formula: C6H3BrF3NO
2-Bromo-5-trifluoromethoxypyridine - Names and Identifiers
| Name | 2-Bromo-5-trifluoromethoxypyridine |
| Synonyms | 2-Bromo-5-(trifluoromethoxy) 2-Bromo-5-trifluoromethoxypyridine Pyridine,2-bromo-5-(trifluoromethoxy)- |
| CAS | 888327-36-4 |
| InChIKey | RKXYQQVLVNEAFB-UHFFFAOYSA-N |
2-Bromo-5-trifluoromethoxypyridine - Physico-chemical Properties
| Molecular Formula | C6H3BrF3NO |
| Molar Mass | 241.99 |
| Density | 1.737±0.06 g/cm3(Predicted) |
| Boling Point | 63-66 °C(Press: 11 Torr) |
| pKa | -3.55±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2-Bromo-5-trifluoromethoxypyridine - Risk and Safety
| Risk Codes | 43 - May cause sensitization by skin contact |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 2810 |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
2-Bromo-5-trifluoromethoxypyridine - Introduction
It is an organic compound with the chemical formula C6H3BrF3NO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
is a solid with a white to light yellow color. Its melting point is about 57-60°C. It is soluble in some organic solvents, such as ethanol and dichloromethane. Its CAS number is 374-22-9.
Use:
It has a wide range of uses in chemical synthesis. It can be used as a raw material or intermediate in organic synthesis for the synthesis of other compounds. Because of its strong electron density and halogen substituents, it can participate in a variety of chemical reactions, such as electrophilic substitution reactions and nucleophilic substitution reactions. These reactions can be used to generate a variety of organic compounds, and have important applications in the field of drug synthesis and material synthesis.
Method:
The method for preparing the pyridine is generally obtained by the reaction of 2-bromo-5-chloromethoxypyridine and trifluoromethanol. Specific synthesis methods include bromination reactions, condensation reactions, and the like. Under laboratory conditions, the reaction process can be controlled by appropriate conditions and reaction conditions to obtain a higher yield of the metal.
Safety Information:
The safety information indicates that it is relatively safe under normal use and storage, but the following items still need to be paid attention:
1. in the operation, should wear appropriate personal protective equipment, such as laboratory gloves, protective glasses and laboratory coat.
2. Avoid contact with skin, eyes and respiratory tract, and avoid inhalation or ingestion of the compound.
3. in storage, it should be stored in a cool, dry place, away from combustibles and oxidants.
Please note that the above information is for reference only, and laboratory safety assessment and operation guidance are required for the specific use of the compound.
Nature:
is a solid with a white to light yellow color. Its melting point is about 57-60°C. It is soluble in some organic solvents, such as ethanol and dichloromethane. Its CAS number is 374-22-9.
Use:
It has a wide range of uses in chemical synthesis. It can be used as a raw material or intermediate in organic synthesis for the synthesis of other compounds. Because of its strong electron density and halogen substituents, it can participate in a variety of chemical reactions, such as electrophilic substitution reactions and nucleophilic substitution reactions. These reactions can be used to generate a variety of organic compounds, and have important applications in the field of drug synthesis and material synthesis.
Method:
The method for preparing the pyridine is generally obtained by the reaction of 2-bromo-5-chloromethoxypyridine and trifluoromethanol. Specific synthesis methods include bromination reactions, condensation reactions, and the like. Under laboratory conditions, the reaction process can be controlled by appropriate conditions and reaction conditions to obtain a higher yield of the metal.
Safety Information:
The safety information indicates that it is relatively safe under normal use and storage, but the following items still need to be paid attention:
1. in the operation, should wear appropriate personal protective equipment, such as laboratory gloves, protective glasses and laboratory coat.
2. Avoid contact with skin, eyes and respiratory tract, and avoid inhalation or ingestion of the compound.
3. in storage, it should be stored in a cool, dry place, away from combustibles and oxidants.
Please note that the above information is for reference only, and laboratory safety assessment and operation guidance are required for the specific use of the compound.
Last Update：2024-04-09 21:04:16
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