2-Bromofuran
2-Bromofuran
CAS: 584-12-3
Molecular Formula: C4H3BrO
2-Bromofuran - Names and Identifiers
| Name | 2-Bromofuran |
| Synonyms | 2-Bromofuran 2-BROMOFURAN 2-Bromofurane 2-Furyl bromide Furan, 2-bromo- alpha-Furyl bromide 2-BROMOETHYLAMINEHYDROBROMIDE 2-Bromofuran (stabilized with CaO) |
| CAS | 584-12-3 |
| InChI | InChI=1/C4H3BrO/c5-4-2-1-3-6-4/h1-3H |
2-Bromofuran - Physico-chemical Properties
| Molecular Formula | C4H3BrO |
| Molar Mass | 146.97 |
| Density | 1.662 |
| Melting Point | 116 °C |
| Boling Point | 52 °C |
| Flash Point | 3°C |
| Vapor Presure | 32.8mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Yellow to Orange |
| Maximum wavelength(λmax) | ['216nm(EtOH)(lit.)'] |
| Sensitive | Light Sensitive |
| Refractive Index | 1.4960 to 1.5000 |
2-Bromofuran - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R11 - Highly Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S3/7 - S9 - Keep container in a well-ventilated place. S16 - Keep away from sources of ignition. S33 - Take precautionary measures against static discharges. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | 1993 |
| Hazard Note | Irritant |
| Hazard Class | 3 |
| Packing Group | II |
2-Bromofuran - Introduction
2-Bromofuran(2-Bromofuran) is an organic compound with the chemical formula C4H3BrO. The following is an introduction to the nature, use, formulation and safety information of 2-Bromofuran:
Nature:
-Appearance: 2-Bromofuran is a colorless to pale yellow liquid.
-Solubility: It can be dissolved in ethanol and ether solvents, slightly soluble in water.
-Melting point:-84°C
-Boiling Point: 121-122°C
-Density: 1.642g/cm³
-Toxicity: 2-Bromofuran has certain toxicity and should be used with caution.
Use:
- 2-Bromofuran is an important organic synthesis intermediate, which is widely used in pharmaceutical synthesis, pesticide synthesis and fragrance synthesis.
-It can be used as a precursor of heterocyclic compounds to prepare biologically active compounds.
Preparation Method:
- 2-Bromofuran can be synthesized by a variety of methods. Common preparation methods include:
1. Reaction of 2,5-dimethoxyfuran and bromine in the presence of a base to generate 2-Bromofuran.
2. 2-Bromofuran is obtained by the reaction of the oxidized bromine with 1,4-isobutadiene.
Safety Information:
- 2-Bromofuran is an organic halogen compound and should be used, stored and handled in accordance with routine laboratory safety procedures.
-It is irritating, and direct contact with skin and eyes may cause irritation and burns.
-Personal protective equipment such as chemical protective gloves, goggles and lab coats should be used during operation to avoid breathing gases or dust.
-Waste shall be disposed of in accordance with local regulations and shall not be dumped.
Nature:
-Appearance: 2-Bromofuran is a colorless to pale yellow liquid.
-Solubility: It can be dissolved in ethanol and ether solvents, slightly soluble in water.
-Melting point:-84°C
-Boiling Point: 121-122°C
-Density: 1.642g/cm³
-Toxicity: 2-Bromofuran has certain toxicity and should be used with caution.
Use:
- 2-Bromofuran is an important organic synthesis intermediate, which is widely used in pharmaceutical synthesis, pesticide synthesis and fragrance synthesis.
-It can be used as a precursor of heterocyclic compounds to prepare biologically active compounds.
Preparation Method:
- 2-Bromofuran can be synthesized by a variety of methods. Common preparation methods include:
1. Reaction of 2,5-dimethoxyfuran and bromine in the presence of a base to generate 2-Bromofuran.
2. 2-Bromofuran is obtained by the reaction of the oxidized bromine with 1,4-isobutadiene.
Safety Information:
- 2-Bromofuran is an organic halogen compound and should be used, stored and handled in accordance with routine laboratory safety procedures.
-It is irritating, and direct contact with skin and eyes may cause irritation and burns.
-Personal protective equipment such as chemical protective gloves, goggles and lab coats should be used during operation to avoid breathing gases or dust.
-Waste shall be disposed of in accordance with local regulations and shall not be dumped.
Last Update：2024-04-09 02:00:47
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