2-Bromoisonicotinamide - Names and Identifiers
2-Bromoisonicotinamide - Physico-chemical Properties
Molecular Formula | C6H5BrN2O
|
Molar Mass | 201.02 |
Density | 1.71g/cm3 |
Melting Point | 192°C |
Boling Point | 338.1°C at 760 mmHg |
Flash Point | 158.3°C |
Vapor Presure | 0.0001mmHg at 25°C |
BRN | 471892 |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.613 |
2-Bromoisonicotinamide - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R36 - Irritating to the eyes
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
Hazard Note | Irritant/Keep Cold |
Hazard Class | IRRITANT |
2-Bromoisonicotinamide - Introduction
It is an organic compound whose chemical formula is C6H5BrN2O. In the structure, the bromine atom is located at the No. 2 Position of the pyridine ring, and the carbamoyl group is located at the No. 4 position of the pyridine ring.
The nature of:
-Appearance: Colorless to light yellow solid
-Melting point: 105-110 ° C
-Boiling point: 381.5 ° C (predicted)
-Solubility: insoluble in water, soluble in organic solvents such as ethanol, dichloromethane
The purpose of:
The compound has a wide range of applications in drug synthesis, and is usually used as an intermediate for the synthesis of various organic compounds and drugs. It can be used to prepare heterocyclic compounds containing thiophene structure and other compounds with biological activity.
Preparation Method:
The compound can be prepared by the reaction of pyridine and bromoformate under alkaline conditions.
The safety information of:
-The compound is toxic and should be handled in accordance with the appropriate safety procedures.
-Contact with skin or eyes may cause irritation and Burns and should be avoided.
-Wear appropriate personal protective equipment during operation, such as lab gloves, goggles, etc.
-During storage and use, avoid contact with oxidants, strong acids and other substances to prevent dangerous reactions.
-Waste should be handled in accordance with local regulations and should not be dumped into sewers or the natural environment.
Last Update:2024-04-09 02:00:45