2-Bromopyridine-3-boronic acid - Names and Identifiers
2-Bromopyridine-3-boronic acid - Physico-chemical Properties
Molecular Formula | C5H5BBrNO2
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Molar Mass | 201.81 |
Density | 1.78±0.1 g/cm3(Predicted) |
Melting Point | 132 °C(dec.) |
Boling Point | 374.3±52.0 °C(Predicted) |
Flash Point | 180.177°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Light yellow |
pKa | 6.61±0.58(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Sensitive | Air Sensitive |
Refractive Index | 1.602 |
MDL | MFCD04113805 |
2-Bromopyridine-3-boronic acid - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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HS Code | 29333990 |
Hazard Note | Irritant/Keep Cold |
Hazard Class | IRRITANT |
2-Bromopyridine-3-boronic acid - Introduction
2-Bromopyridine-3-boronic acid is an organic compound with the chemical formula C5H5BBrNO2. It is the product obtained by the reaction of bromopyridine and boric acid.
2-Bromopyridine-3-boronic acid is a colorless crystalline solid, soluble in some organic solvents such as ethanol and dimethylformamide. It has good stability and storage properties.
2-Bromopyridine-3-boronic acid is mainly used for metal-catalyzed reactions in organic synthesis. It can be used as a precursor of ligand and catalyst, and participate in the reaction similar to Suzuki coupling reaction, and the coupling reaction of organic halogen and aryl boronic acid and other substrates. In addition, it can also be used to prepare other boron-containing organic compounds.
The preparation method of 2-Bromopyridine-3-boronic acid can be obtained by reacting bromopyridine with boric acid. The specific preparation method can refer to the relevant literature and synthesis manual.
Regarding safety information, 2-Bromopyridine-3-boronic acid needs to pay attention to its organic synthesis and safe operation in chemical laboratories. During use, you should follow the laboratory safety procedures, wear personal protective equipment correctly, and avoid direct contact with skin and eyes. During storage and handling, it should be kept away from fire and oxidizing agents and stored in sealed, dry containers. If ingested or inhaled by mistake, please send to hospital or seek medical attention immediately. At the same time, it is also recommended to know the relevant safety data in advance and follow the safety operation guidelines provided by the supplier.
Last Update:2024-04-10 22:29:15