452972-08-6

452972-08-6 - Names and Identifiers

Name	2-Bromopyridine-3-boronic acid
Synonyms	AKOS BRN-0505 2-BROMO-3-PYRIDYLBORONIC ACID 2-Bromopyridine-3-boronic acid 2-BROMOPYRIDINE-3-BORONIC ACID 2-BROMO-3-PYRIDINEBORONIC ACID 2-BROMOPYRIDIN-3-YLBORONIC ACID 2-BROMOPYRIDINE-3-YLBORONIC ACID (2-Bromopyridin-3-yl)boronic acid boronic acid, B-(2-bromo-3-pyridinyl)- Boronic acid, (2-bromo-3-pyridinyl)- (9CI)
CAS	452972-08-6
EINECS	1312995-182-4
InChI	InChI=1/C5H5BBrNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3,9-10H

452972-08-6 - Physico-chemical Properties

Molecular Formula	C5H5BBrNO2
Molar Mass	201.81
Density	1.78±0.1 g/cm3(Predicted)
Melting Point	132 °C(dec.)
Boling Point	374.3±52.0 °C(Predicted)
Flash Point	180.177°C
Vapor Presure	0mmHg at 25°C
Appearance	powder to crystal
Color	White to Light yellow
pKa	6.61±0.58(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Sensitive	Air Sensitive
Refractive Index	1.602
MDL	MFCD04113805

452972-08-6 - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29333990
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

452972-08-6 - Introduction

2-Bromopyridine-3-boronic acid is an organic compound with the chemical formula C5H5BBrNO2. It is the product obtained by the reaction of bromopyridine and boric acid.

2-Bromopyridine-3-boronic acid is a colorless crystalline solid, soluble in some organic solvents such as ethanol and dimethylformamide. It has good stability and storage properties.

2-Bromopyridine-3-boronic acid is mainly used for metal-catalyzed reactions in organic synthesis. It can be used as a precursor of ligand and catalyst, and participate in the reaction similar to Suzuki coupling reaction, and the coupling reaction of organic halogen and aryl boronic acid and other substrates. In addition, it can also be used to prepare other boron-containing organic compounds.

The preparation method of 2-Bromopyridine-3-boronic acid can be obtained by reacting bromopyridine with boric acid. The specific preparation method can refer to the relevant literature and synthesis manual.

Regarding safety information, 2-Bromopyridine-3-boronic acid needs to pay attention to its organic synthesis and safe operation in chemical laboratories. During use, you should follow the laboratory safety procedures, wear personal protective equipment correctly, and avoid direct contact with skin and eyes. During storage and handling, it should be kept away from fire and oxidizing agents and stored in sealed, dry containers. If ingested or inhaled by mistake, please send to hospital or seek medical attention immediately. At the same time, it is also recommended to know the relevant safety data in advance and follow the safety operation guidelines provided by the supplier.

Last Update：2024-04-10 22:29:15