2-Bromothiophene-3-carboxaldehyde

2-Bromothiophene-3-carboxaldehyde - Names and Identifiers

Name	2-Bromothiophene-3-carbaldehyde
Synonyms	2-Bromothiophene-3-carbaldehyde 2-BROMOTHIOPHENE-3-CARBALDEHYDE 2-Bromothiophene-3-carboxaldehyde 2-Bromo-3-thiophenecarboxaldehyde
CAS	1860-99-7

2-Bromothiophene-3-carboxaldehyde - Physico-chemical Properties

Molecular Formula	C5H3BrOS
Molar Mass	191.046
Density	1.789±0.06 g/cm3(Predicted)
Boling Point	60 °C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

2-Bromothiophene-3-carboxaldehyde - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.

2-Bromothiophene-3-carboxaldehyde - Upstream Downstream Industry

Raw Materials

3-Iodo-2-thiophenecarbaldehyde
(2-Bromothien-3-yl)methanol
3-Thiophenecarboxaldehyde ethylene acetal
2-Bromo-3-bromomethylthiophene
THIOPHENE-3-CARBOXALDEHYDE DIETHYL ACETAL
3-Bromothiophene-2-carbaldehyde
2-BROMO-3-IODOTHIOPHENE
3-Methylthiophene
2-Bromo-3-methylthiophene

2-Bromothiophene-3-carboxaldehyde - Introduction

2-Bromo-3-thiophenecarboxaldehyde (-) is an organic compound with the chemical formula C6H4BrOS. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White to light yellow crystal or crystal powder
-Melting Point: 68-70 ℃
-Boiling point: 320-325 ℃
-Density: 1.64g/cm³
-Solubility: Soluble in organic solvents such as ethanol and dimethyl ether

Use:
-2-Bromo-3-thiophenecarboxaldehyde is a commonly used reagent and intermediate in organic synthesis
-It can be used to prepare nucleic acid probes with thiophene-induced nucleotide DNA modification
-In drug synthesis, it is also used as a catalyst and reaction reagent

Method:
2-Bromo-3-thiophenecarboxaldehyde is usually prepared by the following steps:
1.2-bromothiophene is reacted with 3-oxopropionate to obtain 2-bromo-3-thiophene formate.
2. Reduction of 2-bromo-3-thiophene formate to 2-bromo-3-thiophene methanol.
3. Finally, 2-bromo-3-thiophenecarboxaldehyde was obtained by oxidation of 2-bromo-3-thiophenecarboxaldehyde.

Safety Information:
- 2-bromo -3-thiophene formaldehyde may have certain potential hazards to human health, so it is necessary to take appropriate protective measures during operation.
-In case of contact with skin, eyes or respiratory tract, rinse immediately with plenty of water and seek medical help.
-Avoid inhaling powder or creating dust as it may cause irritation to the respiratory tract.
-In storage and handling, should comply with the safety procedures, and properly stored in a cool, dry, well-ventilated environment.

Please note that the use and handling of chemical substances should be carried out under professional guidance and safe laboratory conditions. The above information is for reference only, users should bear the risk.

Last Update：2024-04-09 21:00:56