2-CARBETHOXY-3,5-DIHYDROXYTOLUENE
2,4-DIHYDROXY-6-METHYLBENZOIC ACID ETHYL ESTER
CAS: 2524-37-0
Molecular Formula: C10H12O4
2-CARBETHOXY-3,5-DIHYDROXYTOLUENE - Names and Identifiers
2-CARBETHOXY-3,5-DIHYDROXYTOLUENE - Physico-chemical Properties
| Molecular Formula | C10H12O4 |
| Molar Mass | 196.202 |
| Density | 1.2166 (rough estimate) |
| Melting Point | 129-132 °C(lit.) |
| Boling Point | 293.08°C (rough estimate) |
| pKa | 8.27±0.23(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.5430 (estimate) |
| MDL | MFCD00010821 |
| Physical and Chemical Properties | EPA Chemical Information Benzoic acid, 2,4-dihydroxy-6-methyl-, ethyl ester (2524-37-0) |
| Use | Use machine to synthesize intermediates. |
2-CARBETHOXY-3,5-DIHYDROXYTOLUENE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
2-CARBETHOXY-3,5-DIHYDROXYTOLUENE - Upstream Downstream Industry
2-CARBETHOXY-3,5-DIHYDROXYTOLUENE - Uses and synthesis methods
biological activity
Ethyl Orsellinate is a lichen metabolite, lecanoric acid derivative, with anti-proliferation and anti-tumor activities. Ethyl Orsellinate inhibited the cytotoxic activity of A.salina with LC50 of 495 μM.
in vitro study
Ethyl Orsellinate (0-50 μg/ml; 48 hours) inhibits Hep-2 cells, MCF-7 breast cancer cells, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC 50 s=31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively).
production method
Ethyl 2, 4-dihydroxy-3, 5-dibromo-6-methylbenzoate was added to the sodium hydroxide solution and hydrogenolysis was performed in the presence of a palladium/polyvinyl alcohol catalyst. After the reaction, add sodium chloride to precipitate the catalyst, filter, acidify the filtrate and extract with chloroform, and the extract recovers the solution to obtain ethyl 2, 4-dihydroxy-6-methylbenzoate.
Last Update：2024-04-09 21:00:56
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Product Name: Ethyl orsellinate Visit Supplier Webpage Request for quotationCAS: 2524-37-0
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Spot supply
Product Name: Ethyl orsellinate Visit Supplier Webpage Request for quotationCAS: 2524-37-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for 2-CARBETHOXY-3,5-DIHYDROXYTOLUENE
Chloroform
Poly(vinyl alcohol)
2,4-DIHYDROXY-6-METHYLBENZOIC ACID
ETHYL 3,5-DIBROMO-2,4-DIHYDROXY-6-METHYLBENZOATE
Poly(vinyl alcohol)
2,4-DIHYDROXY-6-METHYLBENZOIC ACID
ETHYL 3,5-DIBROMO-2,4-DIHYDROXY-6-METHYLBENZOATE
Downstream Products for 2-CARBETHOXY-3,5-DIHYDROXYTOLUENE